LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XMD16-144 | 3.33 | uM | LJP5 | 2 | M08 | 72 | hr | 1235 | 1818 | 4356 | 0.4173 | 0.2368 |
| MCF7 | XMD16-144 | 3.33 | uM | LJP5 | 3 | M08 | 72 | hr | 1235 | 1768 | 4326 | 0.4087 | 0.2193 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 1 | M07 | 72 | hr | 1235 | 588 | 4119 | 0.1428 | -0.3477 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 2 | M07 | 72 | hr | 1235 | 849 | 4356 | 0.1949 | -0.1864 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 3 | M07 | 72 | hr | 1235 | 761 | 4326 | 0.1759 | -0.2351 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 1 | M24 | 72 | hr | 1235 | 3403 | 4119 | 0.8261 | 0.7918 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 2 | M24 | 72 | hr | 1235 | 3534 | 4356 | 0.8112 | 0.7826 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 3 | M24 | 72 | hr | 1235 | 3468 | 4326 | 0.8016 | 0.7698 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 1 | M23 | 72 | hr | 1235 | 3592 | 4119 | 0.8720 | 0.8484 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 2 | M23 | 72 | hr | 1235 | 3483 | 4356 | 0.7995 | 0.7684 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 3 | M23 | 72 | hr | 1235 | 3739 | 4326 | 0.8642 | 0.8449 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 1 | M22 | 72 | hr | 1235 | 4247 | 4119 | 1.0310 | 1.0355 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 2 | M22 | 72 | hr | 1235 | 4484 | 4356 | 1.0293 | 1.0320 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 3 | M22 | 72 | hr | 1235 | 4295 | 4326 | 0.9927 | 0.9920 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 1 | M21 | 72 | hr | 1235 | 4097 | 4119 | 0.9946 | 0.9938 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 2 | M21 | 72 | hr | 1235 | 4469 | 4356 | 1.0259 | 1.0283 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 3 | M21 | 72 | hr | 1235 | 4622 | 4326 | 1.0683 | 1.0744 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 1 | M20 | 72 | hr | 1235 | 3932 | 4119 | 0.9546 | 0.9472 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 2 | M20 | 72 | hr | 1235 | 4817 | 4356 | 1.1058 | 1.1137 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 3 | M20 | 72 | hr | 1235 | 4223 | 4326 | 0.9761 | 0.9734 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 1 | M19 | 72 | hr | 1235 | 4103 | 4119 | 0.9961 | 0.9955 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 2 | M19 | 72 | hr | 1235 | 4302 | 4356 | 0.9875 | 0.9863 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 3 | M19 | 72 | hr | 1235 | 4400 | 4326 | 1.0170 | 1.0187 |
| MCF7 | Gefitinib | 0.04 | uM | LJP6 | 1 | N12 | 72 | hr | 1235 | 4441 | 3974 | 1.1175 | 1.1362 |
| MCF7 | Gefitinib | 0.04 | uM | LJP6 | 2 | N12 | 72 | hr | 1235 | 4611 | 4070 | 1.1328 | 1.1504 |