LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 1 | I02 | 72 | hr | 1235 | 2709 | 4119 | 0.6577 | 0.5714 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 2 | I02 | 72 | hr | 1235 | 2764 | 4356 | 0.6345 | 0.5573 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 3 | I02 | 72 | hr | 1235 | 2968 | 4326 | 0.6860 | 0.6237 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 1 | I01 | 72 | hr | 1235 | 1081 | 4119 | 0.2624 | -0.0740 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 2 | I01 | 72 | hr | 1235 | 1150 | 4356 | 0.2640 | -0.0386 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 3 | I01 | 72 | hr | 1235 | 1030 | 4326 | 0.2381 | -0.0957 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 1 | C12 | 72 | hr | 1235 | 4250 | 4119 | 1.0318 | 1.0363 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 2 | C12 | 72 | hr | 1235 | 4174 | 4356 | 0.9582 | 0.9535 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 3 | C12 | 72 | hr | 1235 | 4332 | 4326 | 1.0013 | 1.0014 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 1 | C11 | 72 | hr | 1235 | 4399 | 4119 | 1.0679 | 1.0771 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 2 | C11 | 72 | hr | 1235 | 4195 | 4356 | 0.9630 | 0.9589 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 3 | C11 | 72 | hr | 1235 | 3888 | 4326 | 0.8987 | 0.8852 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 1 | C10 | 72 | hr | 1235 | 4227 | 4119 | 1.0262 | 1.0300 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 2 | C10 | 72 | hr | 1235 | 4065 | 4356 | 0.9331 | 0.9253 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 3 | C10 | 72 | hr | 1235 | 4399 | 4326 | 1.0168 | 1.0185 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 1 | C09 | 72 | hr | 1235 | 3684 | 4119 | 0.8944 | 0.8755 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 2 | C09 | 72 | hr | 1235 | 3781 | 4356 | 0.8679 | 0.8501 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 3 | C09 | 72 | hr | 1235 | 3885 | 4326 | 0.8980 | 0.8844 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 1 | C08 | 72 | hr | 1235 | 3288 | 4119 | 0.7982 | 0.7567 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 2 | C08 | 72 | hr | 1235 | 3230 | 4356 | 0.7415 | 0.6966 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 3 | C08 | 72 | hr | 1235 | 3018 | 4326 | 0.6976 | 0.6388 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 1 | C07 | 72 | hr | 1235 | 1520 | 4119 | 0.3690 | 0.1267 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 2 | C07 | 72 | hr | 1235 | 1608 | 4356 | 0.3691 | 0.1560 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 3 | C07 | 72 | hr | 1235 | 1595 | 4326 | 0.3687 | 0.1518 |
| MCF7 | OSI-027 | 0.04 | uM | LJP6 | 1 | E12 | 72 | hr | 1235 | 3554 | 3974 | 0.8943 | 0.8717 |