LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 3 | F05 | 72 | hr | 1235 | 2502 | 4126 | 0.6064 | 0.5002 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 1 | F04 | 72 | hr | 1235 | 1472 | 3974 | 0.3704 | 0.1096 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 2 | F04 | 72 | hr | 1235 | 1652 | 4070 | 0.4059 | 0.1841 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 3 | F04 | 72 | hr | 1235 | 1736 | 4126 | 0.4207 | 0.2160 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 1 | F03 | 72 | hr | 1235 | 1573 | 3974 | 0.3958 | 0.1541 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 2 | F03 | 72 | hr | 1235 | 1636 | 4070 | 0.4019 | 0.1774 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 3 | F03 | 72 | hr | 1235 | 1768 | 4126 | 0.4285 | 0.2288 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 1 | F02 | 72 | hr | 1235 | 1224 | 3974 | 0.3080 | -0.0055 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 2 | F02 | 72 | hr | 1235 | 1577 | 4070 | 0.3874 | 0.1525 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 3 | F02 | 72 | hr | 1235 | 1442 | 4126 | 0.3495 | 0.0930 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 1 | F01 | 72 | hr | 1235 | 642 | 3974 | 0.1615 | -0.3218 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 2 | F01 | 72 | hr | 1235 | 780 | 4070 | 0.1916 | -0.2346 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 3 | F01 | 72 | hr | 1235 | 778 | 4126 | 0.1885 | -0.2334 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 1 | I06 | 72 | hr | 1235 | 4758 | 4119 | 1.1551 | 1.1730 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 2 | I06 | 72 | hr | 1235 | 4793 | 4356 | 1.1002 | 1.1079 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 3 | I06 | 72 | hr | 1235 | 4847 | 4326 | 1.1203 | 1.1297 |
| MCF7 | AZD-6482 | 0.12 | uM | LJP5 | 1 | I05 | 72 | hr | 1235 | 3646 | 4119 | 0.8851 | 0.8643 |
| MCF7 | AZD-6482 | 0.12 | uM | LJP5 | 2 | I05 | 72 | hr | 1235 | 4063 | 4356 | 0.9327 | 0.9248 |
| MCF7 | AZD-6482 | 0.12 | uM | LJP5 | 3 | I05 | 72 | hr | 1235 | 3842 | 4326 | 0.8880 | 0.8729 |
| MCF7 | AZD-6482 | 0.37 | uM | LJP5 | 1 | I04 | 72 | hr | 1235 | 4231 | 4119 | 1.0271 | 1.0311 |
| MCF7 | AZD-6482 | 0.37 | uM | LJP5 | 2 | I04 | 72 | hr | 1235 | 4115 | 4356 | 0.9446 | 0.9383 |
| MCF7 | AZD-6482 | 0.37 | uM | LJP5 | 3 | I04 | 72 | hr | 1235 | 3775 | 4326 | 0.8725 | 0.8547 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 1 | I03 | 72 | hr | 1235 | 3911 | 4119 | 0.9495 | 0.9412 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 2 | I03 | 72 | hr | 1235 | 4127 | 4356 | 0.9474 | 0.9414 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 3 | I03 | 72 | hr | 1235 | 3981 | 4326 | 0.9202 | 0.9101 |