LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WH-4-025 | 3.33 | uM | LJP5 | 3 | O08 | 72 | hr | 1235 | 1413 | 4326 | 0.3266 | 0.0771 |
| MCF7 | WH-4-025 | 10 | uM | LJP5 | 1 | O07 | 72 | hr | 1235 | 979 | 4119 | 0.2377 | -0.1253 |
| MCF7 | WH-4-025 | 10 | uM | LJP5 | 2 | O07 | 72 | hr | 1235 | 1068 | 4356 | 0.2452 | -0.0770 |
| MCF7 | WH-4-025 | 10 | uM | LJP5 | 3 | O07 | 72 | hr | 1235 | 1084 | 4326 | 0.2506 | -0.0697 |
| MCF7 | R406 | 0.04 | uM | LJP6 | 1 | C18 | 72 | hr | 1235 | 3877 | 3974 | 0.9756 | 0.9709 |
| MCF7 | R406 | 0.04 | uM | LJP6 | 2 | C18 | 72 | hr | 1235 | 4413 | 4070 | 1.0842 | 1.0962 |
| MCF7 | R406 | 0.04 | uM | LJP6 | 3 | C18 | 72 | hr | 1235 | 4030 | 4126 | 0.9767 | 0.9730 |
| MCF7 | R406 | 0.12 | uM | LJP6 | 1 | C17 | 72 | hr | 1235 | 4274 | 3974 | 1.0755 | 1.0882 |
| MCF7 | R406 | 0.12 | uM | LJP6 | 2 | C17 | 72 | hr | 1235 | 4356 | 4070 | 1.0702 | 1.0804 |
| MCF7 | R406 | 0.12 | uM | LJP6 | 3 | C17 | 72 | hr | 1235 | 4666 | 4126 | 1.1308 | 1.1464 |
| MCF7 | R406 | 0.37 | uM | LJP6 | 1 | C16 | 72 | hr | 1235 | 3581 | 3974 | 0.9011 | 0.8802 |
| MCF7 | R406 | 0.37 | uM | LJP6 | 2 | C16 | 72 | hr | 1235 | 3741 | 4070 | 0.9191 | 0.9043 |
| MCF7 | R406 | 0.37 | uM | LJP6 | 3 | C16 | 72 | hr | 1235 | 3523 | 4126 | 0.8538 | 0.8263 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 1 | C15 | 72 | hr | 1235 | 3627 | 3974 | 0.9127 | 0.8944 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 2 | C15 | 72 | hr | 1235 | 3880 | 4070 | 0.9532 | 0.9451 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 3 | C15 | 72 | hr | 1235 | 3693 | 4126 | 0.8950 | 0.8764 |
| MCF7 | R406 | 3.33 | uM | LJP6 | 1 | C14 | 72 | hr | 1235 | 3220 | 3974 | 0.8102 | 0.7653 |
| MCF7 | R406 | 3.33 | uM | LJP6 | 2 | C14 | 72 | hr | 1235 | 3087 | 4070 | 0.7584 | 0.7030 |
| MCF7 | R406 | 3.33 | uM | LJP6 | 3 | C14 | 72 | hr | 1235 | 2855 | 4126 | 0.6919 | 0.6184 |
| MCF7 | R406 | 10 | uM | LJP6 | 1 | C13 | 72 | hr | 1235 | 1734 | 3974 | 0.4363 | 0.2228 |
| MCF7 | R406 | 10 | uM | LJP6 | 2 | C13 | 72 | hr | 1235 | 1672 | 4070 | 0.4108 | 0.1924 |
| MCF7 | R406 | 10 | uM | LJP6 | 3 | C13 | 72 | hr | 1235 | 1863 | 4126 | 0.4515 | 0.2663 |
| MCF7 | BI-2536 | 0.04 | uM | LJP6 | 1 | D18 | 72 | hr | 1235 | 1449 | 3974 | 0.3646 | 0.0992 |
| MCF7 | BI-2536 | 0.04 | uM | LJP6 | 2 | D18 | 72 | hr | 1235 | 1581 | 4070 | 0.3884 | 0.1542 |
| MCF7 | BI-2536 | 0.04 | uM | LJP6 | 3 | D18 | 72 | hr | 1235 | 1539 | 4126 | 0.3730 | 0.1346 |