LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | YM 201636 | 0.04 | uM | LJP5 | 2 | N12 | 72 | hr | 1235 | 4695 | 4356 | 1.0778 | 1.0841 |
| MCF7 | YM 201636 | 0.04 | uM | LJP5 | 3 | N12 | 72 | hr | 1235 | 4919 | 4326 | 1.1370 | 1.1471 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 1 | N11 | 72 | hr | 1235 | 3951 | 4119 | 0.9592 | 0.9526 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 2 | N11 | 72 | hr | 1235 | 4409 | 4356 | 1.0121 | 1.0133 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 3 | N11 | 72 | hr | 1235 | 4404 | 4326 | 1.0179 | 1.0198 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 1 | N10 | 72 | hr | 1235 | 3840 | 4119 | 0.9322 | 0.9208 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 2 | N10 | 72 | hr | 1235 | 4144 | 4356 | 0.9513 | 0.9458 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 3 | N10 | 72 | hr | 1235 | 3660 | 4326 | 0.8460 | 0.8233 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 1 | N09 | 72 | hr | 1235 | 2827 | 4119 | 0.6863 | 0.6104 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 2 | N09 | 72 | hr | 1235 | 2965 | 4356 | 0.6806 | 0.6186 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1235 | 3047 | 4326 | 0.7043 | 0.6475 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 1 | N08 | 72 | hr | 1235 | 2231 | 4119 | 0.5416 | 0.4052 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 2 | N08 | 72 | hr | 1235 | 2212 | 4356 | 0.5078 | 0.3777 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 3 | N08 | 72 | hr | 1235 | 2425 | 4326 | 0.5605 | 0.4521 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 1 | N07 | 72 | hr | 1235 | 1799 | 4119 | 0.4367 | 0.2415 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 2 | N07 | 72 | hr | 1235 | 1882 | 4356 | 0.4320 | 0.2605 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 3 | N07 | 72 | hr | 1235 | 1746 | 4326 | 0.4036 | 0.2108 |
| MCF7 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1235 | 4325 | 4119 | 1.0500 | 1.0569 |
| MCF7 | TWS119 | 0.04 | uM | LJP5 | 2 | M06 | 72 | hr | 1235 | 4782 | 4356 | 1.0977 | 1.1052 |
| MCF7 | TWS119 | 0.04 | uM | LJP5 | 3 | M06 | 72 | hr | 1235 | 5168 | 4326 | 1.1945 | 1.2066 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 1 | M05 | 72 | hr | 1235 | 4549 | 4119 | 1.1043 | 1.1176 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 2 | M05 | 72 | hr | 1235 | 4181 | 4356 | 0.9598 | 0.9553 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 3 | M05 | 72 | hr | 1235 | 3803 | 4326 | 0.8790 | 0.8623 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 1 | M04 | 72 | hr | 1235 | 4256 | 4119 | 1.0332 | 1.0380 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 2 | M04 | 72 | hr | 1235 | 4061 | 4356 | 0.9322 | 0.9243 |