LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 1235 1344 3974 0.3382 0.0513
MCF7 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 1235 1233 4070 0.3029 -0.0011
MCF7 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 1235 1386 4126 0.3359 0.0684
MCF7 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 1235 1301 4119 0.3158 0.0302
MCF7 Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 1235 1399 4356 0.3212 0.0708
MCF7 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 1235 1486 4326 0.3435 0.1076
MCF7 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 1235 1293 3974 0.3254 0.0274
MCF7 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 1235 1517 4070 0.3727 0.1268
MCF7 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 1235 1546 4126 0.3747 0.1376
MCF7 Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 1235 1393 4119 0.3382 0.0716
MCF7 Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 1235 1397 4356 0.3207 0.0700
MCF7 Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 1235 1323 4326 0.3058 0.0386
MCF7 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 1235 1129 3974 0.2841 -0.0520
MCF7 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 1235 1309 4070 0.3216 0.0342
MCF7 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 1235 1288 4126 0.3121 0.0243
MCF7 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 1235 1324 4119 0.3214 0.0407
MCF7 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 1235 1248 4356 0.2865 0.0056
MCF7 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 1235 1321 4326 0.3053 0.0378
MCF7 Geldanamycin
10
uM
LJP6
 1
O01
 72
hr
 1235 479 3974 0.1205 -0.4300
MCF7 Geldanamycin
10
uM
LJP6
 2
O01
 72
hr
 1235 608 4070 0.1494 -0.3378
MCF7 Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 1235 571 4126 0.1384 -0.3583
MCF7 Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 1235 544 4119 0.1321 -0.3763
MCF7 Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 1235 483 4356 0.1109 -0.4034
MCF7 Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 1235 550 4326 0.1271 -0.3608
MCF7 YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 1235 4151 4119 1.0077 1.0089