LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1235 | 2418 | 4119 | 0.5870 | 0.4719 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 2 | L03 | 72 | hr | 1235 | 2675 | 4356 | 0.6141 | 0.5295 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1235 | 2236 | 4326 | 0.5168 | 0.3884 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 1 | L02 | 72 | hr | 1235 | 1210 | 4119 | 0.2938 | -0.0119 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 2 | L02 | 72 | hr | 1235 | 1316 | 4356 | 0.3021 | 0.0354 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 3 | L02 | 72 | hr | 1235 | 1152 | 4326 | 0.2663 | -0.0379 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 1 | L01 | 72 | hr | 1235 | 770 | 4119 | 0.1869 | -0.2382 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 2 | L01 | 72 | hr | 1235 | 646 | 4356 | 0.1483 | -0.2999 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 3 | L01 | 72 | hr | 1235 | 532 | 4326 | 0.1230 | -0.3725 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 1 | P24 | 72 | hr | 1235 | 2020 | 4119 | 0.4904 | 0.3271 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 2 | P24 | 72 | hr | 1235 | 2085 | 4356 | 0.4786 | 0.3336 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 3 | P24 | 72 | hr | 1235 | 2081 | 4326 | 0.4810 | 0.3343 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 1 | P23 | 72 | hr | 1235 | 2108 | 4119 | 0.5118 | 0.3601 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 2 | P23 | 72 | hr | 1235 | 2304 | 4356 | 0.5289 | 0.4089 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 3 | P23 | 72 | hr | 1235 | 2245 | 4326 | 0.5189 | 0.3914 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 1 | P22 | 72 | hr | 1235 | 1927 | 4119 | 0.4678 | 0.2916 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 2 | P22 | 72 | hr | 1235 | 2327 | 4356 | 0.5342 | 0.4166 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 3 | P22 | 72 | hr | 1235 | 2125 | 4326 | 0.4912 | 0.3498 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1235 | 2288 | 4119 | 0.5555 | 0.4258 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 2 | P21 | 72 | hr | 1235 | 2152 | 4356 | 0.4940 | 0.3570 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1235 | 2419 | 4326 | 0.5591 | 0.4501 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 1 | P20 | 72 | hr | 1235 | 2362 | 4119 | 0.5734 | 0.4521 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 2 | P20 | 72 | hr | 1235 | 2399 | 4356 | 0.5507 | 0.4406 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 3 | P20 | 72 | hr | 1235 | 2162 | 4326 | 0.4997 | 0.3628 |
| MCF7 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 1235 | 2050 | 4119 | 0.4977 | 0.3384 |