LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 1 | H12 | 72 | hr | 1235 | 3789 | 3974 | 0.9534 | 0.9442 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 2 | H12 | 72 | hr | 1235 | 4091 | 4070 | 1.0051 | 1.0059 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 3 | H12 | 72 | hr | 1235 | 4263 | 4126 | 1.0331 | 1.0378 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 1 | H11 | 72 | hr | 1235 | 3428 | 3974 | 0.8626 | 0.8321 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 2 | H11 | 72 | hr | 1235 | 3570 | 4070 | 0.8771 | 0.8532 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 3 | H11 | 72 | hr | 1235 | 3719 | 4126 | 0.9013 | 0.8840 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 1 | H10 | 72 | hr | 1235 | 3190 | 3974 | 0.8027 | 0.7555 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 2 | H10 | 72 | hr | 1235 | 2992 | 4070 | 0.7351 | 0.6723 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 3 | H10 | 72 | hr | 1235 | 3401 | 4126 | 0.8242 | 0.7897 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 1 | H09 | 72 | hr | 1235 | 2559 | 3974 | 0.6439 | 0.5404 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 2 | H09 | 72 | hr | 1235 | 3007 | 4070 | 0.7388 | 0.6772 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 3 | H09 | 72 | hr | 1235 | 2796 | 4126 | 0.6776 | 0.5991 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 1 | H08 | 72 | hr | 1235 | 2075 | 3974 | 0.5221 | 0.3602 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 2 | H08 | 72 | hr | 1235 | 1899 | 4070 | 0.4665 | 0.2840 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 3 | H08 | 72 | hr | 1235 | 2271 | 4126 | 0.5504 | 0.4190 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1235 | 418 | 3974 | 0.1052 | -0.4742 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1235 | 419 | 4070 | 0.1029 | -0.4667 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1235 | 454 | 4126 | 0.1100 | -0.4375 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 1 | E18 | 72 | hr | 1235 | 4282 | 4119 | 1.0395 | 1.0451 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 2 | E18 | 72 | hr | 1235 | 4278 | 4356 | 0.9820 | 0.9802 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 3 | E18 | 72 | hr | 1235 | 4142 | 4326 | 0.9574 | 0.9524 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1235 | 4065 | 4119 | 0.9868 | 0.9848 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 2 | E17 | 72 | hr | 1235 | 3504 | 4356 | 0.8044 | 0.7743 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1235 | 3963 | 4326 | 0.9160 | 0.9053 |
| MCF7 | NVP-AEW541 | 0.37 | uM | LJP5 | 1 | E16 | 72 | hr | 1235 | 2588 | 4119 | 0.6283 | 0.5306 |