LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | NVP-AEW541 | 0.37 | uM | LJP5 | 2 | E16 | 72 | hr | 1235 | 2469 | 4356 | 0.5668 | 0.4635 |
| MCF7 | NVP-AEW541 | 0.37 | uM | LJP5 | 3 | E16 | 72 | hr | 1235 | 2572 | 4326 | 0.5945 | 0.5001 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 1 | E15 | 72 | hr | 1235 | 2054 | 4119 | 0.4986 | 0.3399 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 2 | E15 | 72 | hr | 1235 | 2243 | 4356 | 0.5149 | 0.3883 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 3 | E15 | 72 | hr | 1235 | 2172 | 4326 | 0.5020 | 0.3662 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 1 | E14 | 72 | hr | 1235 | 2326 | 4119 | 0.5647 | 0.4394 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 2 | E14 | 72 | hr | 1235 | 2121 | 4356 | 0.4869 | 0.3462 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 3 | E14 | 72 | hr | 1235 | 2190 | 4326 | 0.5062 | 0.3725 |
| MCF7 | NVP-AEW541 | 10 | uM | LJP5 | 1 | E13 | 72 | hr | 1235 | 1143 | 4119 | 0.2775 | -0.0438 |
| MCF7 | NVP-AEW541 | 10 | uM | LJP5 | 2 | E13 | 72 | hr | 1235 | 1107 | 4356 | 0.2541 | -0.0586 |
| MCF7 | NVP-AEW541 | 10 | uM | LJP5 | 3 | E13 | 72 | hr | 1235 | 894 | 4326 | 0.2066 | -0.1638 |
| MCF7 | PHA-665752 | 0.04 | uM | LJP5 | 1 | F18 | 72 | hr | 1235 | 4732 | 4119 | 1.1488 | 1.1662 |
| MCF7 | PHA-665752 | 0.04 | uM | LJP5 | 2 | F18 | 72 | hr | 1235 | 4160 | 4356 | 0.9549 | 0.9499 |
| MCF7 | PHA-665752 | 0.04 | uM | LJP5 | 3 | F18 | 72 | hr | 1235 | 4563 | 4326 | 1.0547 | 1.0598 |
| MCF7 | PHA-665752 | 0.12 | uM | LJP5 | 1 | F17 | 72 | hr | 1235 | 5000 | 4119 | 1.2138 | 1.2360 |
| MCF7 | PHA-665752 | 0.12 | uM | LJP5 | 2 | F17 | 72 | hr | 1235 | 4495 | 4356 | 1.0318 | 1.0348 |
| MCF7 | PHA-665752 | 0.12 | uM | LJP5 | 3 | F17 | 72 | hr | 1235 | 4783 | 4326 | 1.1055 | 1.1141 |
| MCF7 | PHA-665752 | 0.37 | uM | LJP5 | 1 | F16 | 72 | hr | 1235 | 4459 | 4119 | 1.0825 | 1.0934 |
| MCF7 | PHA-665752 | 0.37 | uM | LJP5 | 2 | F16 | 72 | hr | 1235 | 4669 | 4356 | 1.0718 | 1.0777 |
| MCF7 | PHA-665752 | 0.37 | uM | LJP5 | 3 | F16 | 72 | hr | 1235 | 4595 | 4326 | 1.0621 | 1.0677 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 1 | F15 | 72 | hr | 1235 | 4249 | 4119 | 1.0315 | 1.0360 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 2 | F15 | 72 | hr | 1235 | 4227 | 4356 | 0.9703 | 0.9671 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 3 | F15 | 72 | hr | 1235 | 4180 | 4326 | 0.9662 | 0.9623 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 1 | F14 | 72 | hr | 1235 | 3555 | 4119 | 0.8630 | 0.8374 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 2 | F14 | 72 | hr | 1235 | 3834 | 4356 | 0.8801 | 0.8643 |