LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
MCF 10A Imatinib
0.12
uM
LJP6
 1.0082 0.0025 1.0092 0.0028
MCF 10A Celastrol
3.33
uM
LJP6
 0.0383 0.0025 -0.0679 0.0377
SK-BR-3 CGP60474
0.12
uM
LJP6
 0.2446 0.0025 -0.2590 0.0723
MCF 10A Imatinib
0.37
uM
LJP6
 1.0011 0.0025 1.0011 0.0028
Hs 578T SU11274
0.37
uM
LJP5
 0.9572 0.0025 0.9437 0.0050
Hs 578T Ruxolitinib
1.11
uM
LJP5
 0.9619 0.0025 0.9498 0.0054
MCF 10A SNS-032
10.0
uM
LJP6
 0.0342 0.0026 -0.0724 0.0376
MCF 10A NU7441
0.12
uM
LJP5
 0.9970 0.0026 0.9965 0.0031
BT-20 Seliciclib
0.12
uM
LJP5
 1.0141 0.0027 1.0202 0.0036
Hs 578T MK2206
1.11
uM
LJP6
 0.6781 0.0027 0.5774 0.0220
BT-20 Crizotinib
0.37
uM
LJP5
 0.8679 0.0028 0.8084 0.0072
MCF 10A PD173074
0.04
uM
LJP6
 1.0449 0.0028 1.0497 0.0015
SK-BR-3 Dasatinib
0.12
uM
LJP6
 0.9080 0.0030 0.8461 0.0141
BT-20 GSK 690693
0.04
uM
LJP5
 0.8635 0.0030 0.8023 0.0005
Hs 578T PF562271
0.04
uM
LJP6
 0.8864 0.0030 0.8514 0.0027
MCF 10A PHA-665752
0.12
uM
LJP5
 0.9658 0.0031 0.9620 0.0037
SK-BR-3 CGP60474
0.04
uM
LJP6
 0.2549 0.0031 -0.2423 0.0758
Hs 578T Brivanib
1.11
uM
LJP5
 0.9436 0.0032 0.9262 0.0046
MCF 10A Linifanib
0.12
uM
LJP6
 1.0632 0.0033 1.0699 0.0014
MDA-MB-231 PIK-93
10.0
uM
LJP5
 0.4182 0.0033 0.2121 0.0051
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 1.0366 0.0033 1.0495 0.0039
MCF 10A Canertinib
10.0
uM
LJP6
 0.0172 0.0034 -0.0915 0.0402
BT-20 XL147
3.33
uM
LJP5
 0.8869 0.0034 0.8362 0.0045
BT-20 PD0325901
10.0
uM
LJP6
 0.5787 0.0034 0.3896 0.0086
MCF7 XMD11-50
0.12
uM
LJP6
 0.7975 0.0035 0.7188 0.0056