LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1428 | 10605 | 0.1347 | 0.0483 |
| MCF 10A | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 962 | 1760 | 10605 | 0.1660 | 0.0828 |
| MCF 10A | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 962 | 8010 | 10605 | 0.7554 | 0.7310 |
| MCF 10A | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 962 | 872 | 10605 | 0.0823 | -0.0093 |
| MCF 10A | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 962 | 8343 | 10605 | 0.7867 | 0.7654 |
| MCF 10A | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 962 | 1036 | 10605 | 0.0977 | 0.0077 |
| MCF 10A | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 962 | 6186 | 10605 | 0.5834 | 0.5418 |
| MCF 10A | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 962 | 8375 | 10605 | 0.7898 | 0.7688 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 10527 | 10605 | 0.9926 | 0.9919 |
| MCF 10A | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 962 | 926 | 10605 | 0.0873 | -0.0037 |
| MCF 10A | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 962 | 8711 | 10605 | 0.8214 | 0.8036 |
| MCF 10A | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 10191 | 10605 | 0.9610 | 0.9571 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9905 | 10605 | 0.9341 | 0.9275 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 962 | 11416 | 10605 | 1.0765 | 1.0842 |
| MCF 10A | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9492 | 10605 | 0.8951 | 0.8846 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 962 | 884 | 10605 | 0.0834 | -0.0081 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 962 | 819 | 10605 | 0.0772 | -0.0148 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 962 | 8441 | 10605 | 0.7959 | 0.7756 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1596 | 10605 | 0.1506 | 0.0658 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9491 | 10605 | 0.8950 | 0.8845 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 962 | 10613 | 10605 | 1.0008 | 1.0009 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9609 | 10605 | 0.9061 | 0.8967 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1409 | 10605 | 0.1329 | 0.0463 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 962 | 5457 | 10605 | 0.5146 | 0.4662 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 962 | 4339 | 10605 | 0.4091 | 0.3502 |