LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1810 | 10605 | 0.1707 | 0.0880 |
| MCF 10A | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 962 | 1369 | 10605 | 0.1292 | 0.0423 |
| MCF 10A | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 962 | 10573 | 10605 | 0.9970 | 0.9967 |
| MCF 10A | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 962 | 3432 | 10605 | 0.3237 | 0.2562 |
| MCF 10A | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1405 | 10605 | 0.1326 | 0.0460 |
| MCF 10A | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1275 | 10605 | 0.1203 | 0.0325 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 962 | 5086 | 10605 | 0.4796 | 0.4277 |
| MCF 10A | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 962 | 2906 | 10605 | 0.2741 | 0.2017 |
| MCF 10A | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 962 | 10157 | 10605 | 0.9578 | 0.9535 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 962 | 847 | 10605 | 0.0799 | -0.0119 |
| MCF 10A | PI103 | 1.11 | uM | LJP6 | 72 | hr | 962 | 1511 | 10605 | 0.1425 | 0.0569 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9201 | 10605 | 0.8676 | 0.8544 |
| MCF 10A | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 962 | 6839 | 10605 | 0.6449 | 0.6095 |
| MCF 10A | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 962 | 6339 | 10605 | 0.5977 | 0.5576 |
| MCF 10A | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 962 | 1367 | 10605 | 0.1289 | 0.0420 |
| MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 962 | 1324 | 10605 | 0.1249 | 0.0376 |
| MCF 10A | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9451 | 10605 | 0.8912 | 0.8804 |
| MCF 10A | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9887 | 10605 | 0.9323 | 0.9255 |
| MCF 10A | XL147 | 1.11 | uM | LJP5 | 72 | hr | 962 | 8797 | 10605 | 0.8295 | 0.8125 |
| MCF 10A | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 8216 | 10605 | 0.7748 | 0.7523 |
| MCF 10A | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 2544 | 10605 | 0.2400 | 0.1641 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 962 | 9424 | 10605 | 0.8887 | 0.8776 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 962 | 9467 | 10605 | 0.8928 | 0.8820 |
| MCF 10A | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 962 | 8235 | 10605 | 0.7766 | 0.7543 |
| MCF 10A | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 7838 | 10605 | 0.7391 | 0.7131 |