LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 962 6712 10605 0.6329 0.5963
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 962 9832 10605 0.9272 0.9199
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 962 9724 10605 0.9170 0.9087
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 962 10735 10605 1.0123 1.0135
MCF 10A JNK-9L
0.12
uM
LJP6
 72
hr
 962 9821 10605 0.9261 0.9188
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 962 10510 10605 0.9911 0.9902
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 962 10580 10605 0.9976 0.9974
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 962 10166 10605 0.9586 0.9545
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 962 11286 10605 1.0642 1.0706
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 962 10395 10605 0.9802 0.9782
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 962 1047 10605 0.0987 0.0088
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 962 1024 10605 0.0966 0.0064
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 962 9561 10605 0.9016 0.8917
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 962 3269 10605 0.3083 0.2392
MCF 10A Nilotinib
0.12
uM
LJP5
 72
hr
 962 9650 10605 0.9100 0.9010
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 962 10709 10605 1.0099 1.0108
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 962 10592 10605 0.9988 0.9986
MCF 10A Dactolisib
0.12
uM
LJP5
 72
hr
 962 1537 10605 0.1450 0.0596
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 962 8136 10605 0.7672 0.7440
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 962 5870 10605 0.5535 0.5090
MCF 10A PD0325901
0.12
uM
LJP5
 72
hr
 962 1928 10605 0.1818 0.1002
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 962 1884 10605 0.1777 0.0956
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 962 10757 10605 1.0144 1.0158
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 962 4935 10605 0.4654 0.4121
MCF 10A Pelitinib
0.12
uM
LJP5
 72
hr
 962 1400 10605 0.1321 0.0455