LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 962 | 10394 | 10605 | 0.9802 | 0.9782 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 962 | 1833 | 10605 | 0.1729 | 0.0904 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 962 | 1653 | 10605 | 0.1559 | 0.0717 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 962 | 1023 | 10605 | 0.0965 | 0.0063 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 962 | 2737 | 10605 | 0.2581 | 0.1841 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 962 | 1600 | 10605 | 0.1509 | 0.0662 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 962 | 1137 | 10605 | 0.1072 | 0.0181 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 962 | 7264 | 10605 | 0.6850 | 0.6536 |
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 962 | 1578 | 10605 | 0.1488 | 0.0639 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 962 | 752 | 10605 | 0.0709 | -0.0218 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 962 | 413 | 10605 | 0.0389 | -0.0570 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 962 | 821 | 10605 | 0.0774 | -0.0146 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 962 | 369 | 10605 | 0.0348 | -0.0615 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 962 | 5979 | 10605 | 0.5639 | 0.5203 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 962 | 359 | 10605 | 0.0339 | -0.0625 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 72 | hr | 962 | 1120 | 10605 | 0.1057 | 0.0164 |
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 962 | 8942 | 10605 | 0.8432 | 0.8276 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 962 | 587 | 10605 | 0.0554 | -0.0389 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 962 | 522 | 10605 | 0.0492 | -0.0456 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 962 | 495 | 10605 | 0.0467 | -0.0484 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 962 | 381 | 10605 | 0.0360 | -0.0602 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 962 | 4858 | 10605 | 0.4581 | 0.4040 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 962 | 7375 | 10605 | 0.6954 | 0.6650 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 72 | hr | 962 | 4368 | 10605 | 0.4119 | 0.3532 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 962 | 1343 | 10605 | 0.1267 | 0.0396 |