LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1778 | 4093 | 0.4345 | 0.1973 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4189 | 4093 | 1.0236 | 1.0335 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4206 | 4093 | 1.0276 | 1.0392 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4346 | 4093 | 1.0618 | 1.0877 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3308 | 4093 | 0.8082 | 0.7278 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 2770 | 4093 | 0.6769 | 0.5414 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1209 | 2235 | 4093 | 0.5462 | 0.3559 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3886 | 4093 | 0.9495 | 0.9283 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4202 | 4093 | 1.0266 | 1.0378 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3749 | 4093 | 0.9160 | 0.8807 |
| MCF7 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3699 | 4093 | 0.9037 | 0.8634 |
| MCF7 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1411 | 4093 | 0.3448 | 0.0700 |
| MCF7 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 1014 | 4093 | 0.2477 | -0.0678 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 1412 | 4093 | 0.3451 | 0.0703 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 2030 | 4093 | 0.4961 | 0.2847 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3957 | 4093 | 0.9669 | 0.9531 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4214 | 4093 | 1.0296 | 1.0421 |
| MCF7 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4381 | 4093 | 1.0704 | 1.1000 |
| MCF7 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3460 | 4093 | 0.8454 | 0.7805 |
| MCF7 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1264 | 4093 | 0.3089 | 0.0190 |
| MCF7 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 622 | 4093 | 0.1520 | -0.2038 |
| MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3292 | 4093 | 0.8044 | 0.7223 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 4310 | 4093 | 1.0530 | 1.0753 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3938 | 4093 | 0.9623 | 0.9465 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1575 | 4093 | 0.3850 | 0.1270 |