LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1209 3723 4093 0.9096 0.8717
MCF7 Sigma A6730
0.37
uM
LJP5
 72
hr
 1209 2824 4093 0.6901 0.5601
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1209 643 4093 0.1572 -0.1964
MCF7 AT-7519
0.37
uM
LJP6
 72
hr
 1209 604 4093 0.1477 -0.2098
MCF7 AZD 5438
0.37
uM
LJP6
 72
hr
 1209 1175 4093 0.2872 -0.0119
MCF7 AZD-6482
0.37
uM
LJP5
 72
hr
 1209 4050 4093 0.9895 0.9851
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1209 1453 4093 0.3552 0.0847
MCF7 AZD8055
0.37
uM
LJP6
 72
hr
 1209 1030 4093 0.2517 -0.0622
MCF7 AZD8330
0.37
uM
LJP5
 72
hr
 1209 2162 4093 0.5283 0.3304
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1209 1454 4093 0.3552 0.0848
MCF7 BI-2536
0.37
uM
LJP6
 72
hr
 1209 1305 4093 0.3190 0.0333
MCF7 BMS345541
0.37
uM
LJP6
 72
hr
 1209 3399 4093 0.8305 0.7594
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1209 723 4093 0.1766 -0.1687
MCF7 GDC-0980
0.37
uM
LJP5
 72
hr
 1209 1023 4093 0.2501 -0.0645
MCF7 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1209 2349 4093 0.5740 0.3953
MCF7 SB590885
0.37
uM
LJP5
 72
hr
 1209 4099 4093 1.0016 1.0023
MCF7 PIK-93
0.37
uM
LJP5
 72
hr
 1209 3322 4093 0.8116 0.7326
MCF7 KIN001-043
0.37
uM
LJP6
 72
hr
 1209 3159 4093 0.7719 0.6762
MCF7 Alpelisib
0.37
uM
LJP5
 72
hr
 1209 2069 4093 0.5056 0.2982
MCF7 Luminespib
0.37
uM
LJP5
 72
hr
 1209 1235 4093 0.3018 0.0089
MCF7 A443654
0.37
uM
LJP6
 72
hr
 1209 491 4093 0.1200 -0.2492
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1209 1958 4093 0.4785 0.2597
MCF7 XMD11-85h
0.37
uM
LJP6
 72
hr
 1209 3735 4093 0.9126 0.8760
MCF7 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1209 4185 4093 1.0226 1.0321
MCF7 WH-4-025
0.37
uM
LJP5
 72
hr
 1209 2661 4093 0.6503 0.5036