LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 962 | 7948 | 10605 | 0.7495 | 0.7245 |
| MCF 10A | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1438 | 10605 | 0.1356 | 0.0494 |
| MCF 10A | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9258 | 10605 | 0.8730 | 0.8603 |
| MCF 10A | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 962 | 6073 | 10605 | 0.5727 | 0.5301 |
| MCF 10A | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1658 | 10605 | 0.1564 | 0.0722 |
| MCF 10A | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 2192 | 10605 | 0.2068 | 0.1276 |
| MCF 10A | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 962 | 959 | 10605 | 0.0905 | -0.0003 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 962 | 245 | 10605 | 0.0231 | -0.0743 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 962 | 236 | 10605 | 0.0223 | -0.0752 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 962 | 11066 | 10605 | 1.0435 | 1.0478 |
| MCF 10A | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 962 | 10368 | 10605 | 0.9777 | 0.9755 |
| MCF 10A | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 962 | 10248 | 10605 | 0.9663 | 0.9630 |
| MCF 10A | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9096 | 10605 | 0.8578 | 0.8436 |
| MCF 10A | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 7297 | 10605 | 0.6881 | 0.6569 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1923 | 10605 | 0.1814 | 0.0997 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 1272 | 10605 | 0.1200 | 0.0322 |
| MCF 10A | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1676 | 10605 | 0.1581 | 0.0741 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 962 | 11253 | 10605 | 1.0611 | 1.0672 |
| MCF 10A | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1460 | 10605 | 0.1377 | 0.0517 |
| MCF 10A | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 962 | 2756 | 10605 | 0.2599 | 0.1860 |
| MCF 10A | R406 | 1.11 | uM | LJP6 | 72 | hr | 962 | 9076 | 10605 | 0.8558 | 0.8414 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 962 | 4104 | 10605 | 0.3871 | 0.3259 |
| MCF 10A | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 1470 | 10605 | 0.1386 | 0.0527 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 962 | 815 | 10605 | 0.0769 | -0.0152 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 962 | 711 | 10605 | 0.0671 | -0.0260 |