LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 962 10337 10605 0.9747 0.9722
MCF 10A AZD7762
0.12
uM
LJP6
 72
hr
 962 8295 10605 0.7822 0.7605
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 962 2256 10605 0.2128 0.1342
MCF 10A AZD8330
0.12
uM
LJP5
 72
hr
 962 1687 10605 0.1591 0.0752
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 962 1429 10605 0.1348 0.0484
MCF 10A BI-2536
0.12
uM
LJP6
 72
hr
 962 898 10605 0.0847 -0.0067
MCF 10A BMS345541
0.12
uM
LJP6
 72
hr
 962 10223 10605 0.9640 0.9604
MCF 10A SNS-032
0.12
uM
LJP6
 72
hr
 962 1209 10605 0.1140 0.0256
MCF 10A GDC-0980
0.12
uM
LJP5
 72
hr
 962 4274 10605 0.4030 0.3435
MCF 10A NVP-AEW541
0.12
uM
LJP5
 72
hr
 962 10266 10605 0.9681 0.9649
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 962 8893 10605 0.8386 0.8225
MCF 10A PIK-93
0.12
uM
LJP5
 72
hr
 962 10035 10605 0.9463 0.9410
MCF 10A KIN001-043
0.12
uM
LJP6
 72
hr
 962 9752 10605 0.9196 0.9116
MCF 10A Alpelisib
0.12
uM
LJP5
 72
hr
 962 10278 10605 0.9692 0.9661
MCF 10A Luminespib
0.12
uM
LJP5
 72
hr
 962 783 10605 0.0739 -0.0185
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 962 7796 10605 0.7352 0.7087
MCF 10A OSI-027
0.12
uM
LJP6
 72
hr
 962 4669 10605 0.4403 0.3845
MCF 10A XMD11-85h
0.12
uM
LJP6
 72
hr
 962 10944 10605 1.0320 1.0351
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 962 10055 10605 0.9482 0.9430
MCF 10A WH-4-025
0.12
uM
LJP5
 72
hr
 962 9320 10605 0.8788 0.8667
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 962 9948 10605 0.9381 0.9319
MCF 10A XMD16-144
0.12
uM
LJP5
 72
hr
 962 1452 10605 0.1369 0.0508
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 962 10506 10605 0.9907 0.9898
MCF 10A Buparlisib
0.12
uM
LJP5
 72
hr
 962 10235 10605 0.9651 0.9616
MCF 10A BX-912
0.12
uM
LJP5
 72
hr
 962 8016 10605 0.7559 0.7315