LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1559 | 5578 | 0.2795 | -0.3242 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5210 | 5578 | 0.9340 | 0.8788 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1573 | 5578 | 0.2820 | -0.3196 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2423 | 5578 | 0.4345 | -0.0395 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5618 | 5578 | 1.0072 | 1.0132 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 6223 | 5578 | 1.1156 | 1.2125 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 6126 | 5578 | 1.0982 | 1.1805 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5207 | 5578 | 0.9334 | 0.8777 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5068 | 5578 | 0.9085 | 0.8318 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2191 | 5578 | 0.3928 | -0.1160 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1373 | 5578 | 0.2462 | -0.3855 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3457 | 5578 | 0.6198 | 0.3012 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4685 | 5578 | 0.8398 | 0.7056 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5967 | 5578 | 1.0697 | 1.1281 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5617 | 5578 | 1.0069 | 1.0126 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3543 | 5578 | 0.6352 | 0.3295 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2098 | 5578 | 0.3761 | -0.1468 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4962 | 5578 | 0.8895 | 0.7968 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4773 | 5578 | 0.8557 | 0.7348 |
| SK-BR-3 | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5148 | 5578 | 0.9229 | 0.8583 |
| SK-BR-3 | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2262 | 5578 | 0.4055 | -0.0926 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5058 | 5578 | 0.9068 | 0.8287 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4768 | 5578 | 0.8547 | 0.7330 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1367 | 5578 | 0.2451 | -0.3875 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4297 | 5578 | 0.7703 | 0.5777 |