LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 4487 | 5578 | 0.8044 | 0.6404 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2070 | 5578 | 0.3711 | -0.1559 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1780 | 5578 | 0.3191 | -0.2515 |
| SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1796 | 5578 | 0.3220 | -0.2462 |
| SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3685 | 5578 | 0.6606 | 0.3762 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5944 | 5578 | 1.0656 | 1.1206 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5654 | 5578 | 1.0136 | 1.0250 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5691 | 5578 | 1.0203 | 1.0372 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5809 | 5578 | 1.0413 | 1.0759 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2445 | 5578 | 0.4383 | -0.0324 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1222 | 5578 | 0.2191 | -0.4353 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4144 | 5578 | 0.7430 | 0.5275 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4425 | 5578 | 0.7933 | 0.6201 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6054 | 5578 | 1.0853 | 1.1567 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5056 | 5578 | 0.9064 | 0.8279 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1683 | 5578 | 0.3018 | -0.2833 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4904 | 5578 | 0.8791 | 0.7778 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1157 | 5578 | 0.2074 | -0.4568 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3234 | 5578 | 0.5798 | 0.2277 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4292 | 5578 | 0.7694 | 0.5762 |
| SK-BR-3 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5521 | 5578 | 0.9898 | 0.9812 |
| SK-BR-3 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1690 | 5578 | 0.3029 | -0.2812 |
| SK-BR-3 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1763 | 5578 | 0.3161 | -0.2569 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4441 | 5578 | 0.7961 | 0.6252 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2088 | 5578 | 0.3744 | -0.1498 |