LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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MDA-MB-231 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1477 | 5013 | 0.2947 | 0.0447 |
MDA-MB-231 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 3020 | 5013 | 0.6024 | 0.4615 |
MDA-MB-231 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1954 | 5013 | 0.3899 | 0.1737 |
MDA-MB-231 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4709 | 5013 | 0.9394 | 0.9179 |
MDA-MB-231 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1055 | 5013 | 0.2104 | -0.0694 |
MDA-MB-231 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1907 | 5013 | 0.3804 | 0.1608 |
MDA-MB-231 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4469 | 5013 | 0.8915 | 0.8531 |
MDA-MB-231 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 3250 | 5013 | 0.6483 | 0.5237 |
MDA-MB-231 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1421 | 5013 | 0.2834 | 0.0295 |
MDA-MB-231 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1193 | 5013 | 0.2380 | -0.0320 |
MDA-MB-231 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1216 | 5013 | 0.2425 | -0.0259 |
MDA-MB-231 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4584 | 5013 | 0.9144 | 0.8841 |
MDA-MB-231 | Ruxolitinib | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4987 | 5013 | 0.9947 | 0.9928 |
MDA-MB-231 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4835 | 5013 | 0.9645 | 0.9519 |
MDA-MB-231 | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 1311 | 2384 | 5013 | 0.4755 | 0.2897 |
MDA-MB-231 | Selumetinib | 3.33 | uM | LJP6 | 72 | hr | 1311 | 2116 | 5013 | 0.4221 | 0.2174 |
MDA-MB-231 | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 1311 | 4259 | 5013 | 0.8496 | 0.7964 |
MDA-MB-231 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1311 | 4776 | 5013 | 0.9528 | 0.9360 |
MDA-MB-231 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4421 | 5013 | 0.8818 | 0.8399 |
MDA-MB-231 | Fedratinib | 3.33 | uM | LJP5 | 72 | hr | 1311 | 2223 | 5013 | 0.4434 | 0.2462 |
MDA-MB-231 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 3466 | 5013 | 0.6913 | 0.5820 |
MDA-MB-231 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1568 | 5013 | 0.3129 | 0.0694 |
MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1450 | 5013 | 0.2892 | 0.0374 |
MDA-MB-231 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1514 | 5013 | 0.3021 | 0.0547 |
MDA-MB-231 | Trametinib | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1754 | 5013 | 0.3500 | 0.1197 |