LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PF431396
3.33
uM
LJP5
72
hr
1311 1477 5013 0.2947 0.0447
MDA-MB-231 PF477736
3.33
uM
LJP5
72
hr
1311 3020 5013 0.6024 0.4615
MDA-MB-231 PF562271
3.33
uM
LJP6
72
hr
1311 1954 5013 0.3899 0.1737
MDA-MB-231 PHA-665752
3.33
uM
LJP5
72
hr
1311 4709 5013 0.9394 0.9179
MDA-MB-231 PHA-793887
3.33
uM
LJP6
72
hr
1311 1055 5013 0.2104 -0.0694
MDA-MB-231 PI103
3.33
uM
LJP6
72
hr
1311 1907 5013 0.3804 0.1608
MDA-MB-231 PLX-4720
3.33
uM
LJP5
72
hr
1311 4469 5013 0.8915 0.8531
MDA-MB-231 QL-X-138
3.33
uM
LJP6
72
hr
1311 3250 5013 0.6483 0.5237
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
72
hr
1311 1421 5013 0.2834 0.0295
MDA-MB-231 Radicicol
3.33
uM
LJP5
72
hr
1311 1193 5013 0.2380 -0.0320
MDA-MB-231 Radicicol
3.33
uM
LJP6
72
hr
1311 1216 5013 0.2425 -0.0259
MDA-MB-231 Seliciclib
3.33
uM
LJP5
72
hr
1311 4584 5013 0.9144 0.8841
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
72
hr
1311 4987 5013 0.9947 0.9928
MDA-MB-231 XL147
3.33
uM
LJP5
72
hr
1311 4835 5013 0.9645 0.9519
MDA-MB-231 Saracatinib
3.33
uM
LJP6
72
hr
1311 2384 5013 0.4755 0.2897
MDA-MB-231 Selumetinib
3.33
uM
LJP6
72
hr
1311 2116 5013 0.4221 0.2174
MDA-MB-231 Sirolimus
3.33
uM
LJP6
72
hr
1311 4259 5013 0.8496 0.7964
MDA-MB-231 Sorafenib
3.33
uM
LJP6
72
hr
1311 4776 5013 0.9528 0.9360
MDA-MB-231 SU11274
3.33
uM
LJP5
72
hr
1311 4421 5013 0.8818 0.8399
MDA-MB-231 Fedratinib
3.33
uM
LJP5
72
hr
1311 2223 5013 0.4434 0.2462
MDA-MB-231 TGX221
3.33
uM
LJP5
72
hr
1311 3466 5013 0.6913 0.5820
MDA-MB-231 Torin1
3.33
uM
LJP6
72
hr
1311 1568 5013 0.3129 0.0694
MDA-MB-231 Torin2
3.33
uM
LJP5
72
hr
1311 1450 5013 0.2892 0.0374
MDA-MB-231 Tozasertib
3.33
uM
LJP5
72
hr
1311 1514 5013 0.3021 0.0547
MDA-MB-231 Trametinib
3.33
uM
LJP5
72
hr
1311 1754 5013 0.3500 0.1197