LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5513 | 5578 | 0.9882 | 0.9784 |
SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1345 | 5578 | 0.2412 | -0.3947 |
SK-BR-3 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1906 | 5578 | 0.3417 | -0.2100 |
SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 4838 | 5578 | 0.8672 | 0.7560 |
SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2087 | 5578 | 0.3741 | -0.1504 |
SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1439 | 5578 | 0.2580 | -0.3639 |
SK-BR-3 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4184 | 5578 | 0.7501 | 0.5406 |
SK-BR-3 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1181 | 5578 | 0.2117 | -0.4489 |
SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1909 | 5578 | 0.3423 | -0.2088 |
SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5537 | 5578 | 0.9927 | 0.9865 |
SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 6185 | 5578 | 1.1087 | 1.1998 |
SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5700 | 5578 | 1.0219 | 1.0402 |
SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4273 | 5578 | 0.7660 | 0.5698 |
SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 4334 | 5578 | 0.7769 | 0.5899 |
SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2289 | 5578 | 0.4104 | -0.0837 |
SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1204 | 5578 | 0.2159 | -0.4411 |
SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2274 | 5578 | 0.4077 | -0.0886 |
SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4492 | 5578 | 0.8052 | 0.6420 |
SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4412 | 5578 | 0.7910 | 0.6158 |
SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5260 | 5578 | 0.9429 | 0.8951 |
SK-BR-3 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2903 | 5578 | 0.5204 | 0.1185 |
SK-BR-3 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2158 | 5578 | 0.3870 | -0.1268 |
SK-BR-3 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5216 | 5578 | 0.9350 | 0.8805 |
SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1453 | 5578 | 0.2605 | -0.3592 |
SK-BR-3 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2125 | 5578 | 0.3809 | -0.1379 |