LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2873 | 5578 | 0.5150 | 0.1086 |
| SK-BR-3 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5836 | 5578 | 1.0462 | 1.0850 |
| SK-BR-3 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4865 | 5578 | 0.8722 | 0.7651 |
| SK-BR-3 | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4992 | 5578 | 0.8949 | 0.8068 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5449 | 5578 | 0.9768 | 0.9574 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5032 | 5578 | 0.9021 | 0.8200 |
| SK-BR-3 | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4521 | 5578 | 0.8105 | 0.6518 |
| SK-BR-3 | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5924 | 5578 | 1.0619 | 1.1138 |
| SK-BR-3 | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5536 | 5578 | 0.9924 | 0.9859 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5279 | 5578 | 0.9463 | 0.9014 |
| SK-BR-3 | R406 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5197 | 5578 | 0.9316 | 0.8743 |
| SK-BR-3 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3061 | 5578 | 0.5488 | 0.1707 |
| SK-BR-3 | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4547 | 5578 | 0.8151 | 0.6602 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1929 | 5578 | 0.3458 | -0.2024 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2073 | 5578 | 0.3717 | -0.1548 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5599 | 5578 | 1.0036 | 1.0067 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4327 | 5578 | 0.7757 | 0.5877 |
| SK-BR-3 | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4993 | 5578 | 0.8951 | 0.8072 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1684 | 5578 | 0.3019 | -0.2831 |
| SK-BR-3 | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4320 | 5578 | 0.7744 | 0.5854 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4493 | 5578 | 0.8055 | 0.6425 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5155 | 5578 | 0.9242 | 0.8606 |
| SK-BR-3 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4198 | 5578 | 0.7525 | 0.5451 |
| SK-BR-3 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5504 | 5578 | 0.9867 | 0.9756 |
| SK-BR-3 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4937 | 5578 | 0.8851 | 0.7888 |