LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TWS119
3.33
uM
LJP5
 72
hr
 1311 3457 5013 0.6897 0.5797
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 72
hr
 1311 4060 5013 0.8099 0.7426
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 1311 1037 5013 0.2069 -0.0741
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1311 810 5013 0.1616 -0.1354
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 72
hr
 1311 1859 5013 0.3708 0.1478
MDA-MB-231 WZ3105
3.33
uM
LJP5
 72
hr
 1311 818 5013 0.1632 -0.1334
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 72
hr
 1311 1905 5013 0.3800 0.1603
MDA-MB-231 Y39983
3.33
uM
LJP6
 72
hr
 1311 3431 5013 0.6844 0.5725
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 1311 3739 5013 0.7459 0.6558
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 72
hr
 1311 2945 5013 0.5875 0.4413
MDA-MB-231 Afatinib
10.0
uM
LJP6
 72
hr
 1311 808 5013 0.1613 -0.1359
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 72
hr
 1311 3636 5013 0.7253 0.6280
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 72
hr
 1311 680 5013 0.1357 -0.1706
MDA-MB-231 AT-7519
10.0
uM
LJP6
 72
hr
 1311 524 5013 0.1046 -0.2127
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 72
hr
 1311 652 5013 0.1301 -0.1781
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 72
hr
 1311 3001 5013 0.5987 0.4564
MDA-MB-231 AZD7762
10.0
uM
LJP6
 72
hr
 1311 716 5013 0.1428 -0.1609
MDA-MB-231 AZD8055
10.0
uM
LJP6
 72
hr
 1311 1562 5013 0.3117 0.0678
MDA-MB-231 AZD8330
10.0
uM
LJP5
 72
hr
 1311 1587 5013 0.3165 0.0744
MDA-MB-231 Barasertib
10.0
uM
LJP5
 72
hr
 1311 1507 5013 0.3007 0.0529
MDA-MB-231 BI-2536
10.0
uM
LJP6
 72
hr
 1311 1245 5013 0.2485 -0.0178
MDA-MB-231 BMS345541
10.0
uM
LJP6
 72
hr
 1311 778 5013 0.1553 -0.1441
MDA-MB-231 SNS-032
10.0
uM
LJP6
 72
hr
 1311 818 5013 0.1632 -0.1333
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 72
hr
 1311 1738 5013 0.3468 0.1153
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 72
hr
 1311 2246 5013 0.4481 0.2526