LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PI103
0.37
uM
LJP6
 72
hr
 1311 3001 5013 0.5987 0.4564
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 1311 5164 5013 1.0301 1.0408
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 72
hr
 1311 4191 5013 0.8360 0.7779
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 72
hr
 1311 2885 5013 0.5755 0.4251
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 1311 2498 5013 0.4983 0.3206
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1311 2483 5013 0.4953 0.3165
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 72
hr
 1311 4845 5013 0.9665 0.9546
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1311 5229 5013 1.0431 1.0584
MDA-MB-231 XL147
0.37
uM
LJP5
 72
hr
 1311 4849 5013 0.9673 0.9557
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 1311 2910 5013 0.5804 0.4318
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 72
hr
 1311 2820 5013 0.5626 0.4076
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 1311 4250 5013 0.8477 0.7937
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 72
hr
 1311 4824 5013 0.9623 0.9489
MDA-MB-231 SU11274
0.37
uM
LJP5
 72
hr
 1311 5082 5013 1.0137 1.0186
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 72
hr
 1311 4886 5013 0.9746 0.9656
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 1311 4516 5013 0.9008 0.8656
MDA-MB-231 Torin1
0.37
uM
LJP6
 72
hr
 1311 1984 5013 0.3959 0.1818
MDA-MB-231 Torin2
0.37
uM
LJP5
 72
hr
 1311 1576 5013 0.3145 0.0716
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 1311 1469 5013 0.2930 0.0425
MDA-MB-231 Trametinib
0.37
uM
LJP5
 72
hr
 1311 1682 5013 0.3356 0.1002
MDA-MB-231 TWS119
0.37
uM
LJP5
 72
hr
 1311 4706 5013 0.9388 0.9171
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 72
hr
 1311 4824 5013 0.9622 0.9488
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 1311 4318 5013 0.8614 0.8123
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 1311 3880 5013 0.7739 0.6938
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 72
hr
 1311 2150 5013 0.4289 0.2265