LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 SB590885
0.12
uM
LJP5
 72
hr
 1235 4368 4156 1.0510 1.0726
MCF7 PIK-93
0.12
uM
LJP5
 72
hr
 1235 4937 4156 1.1880 1.2676
MCF7 KIN001-043
0.12
uM
LJP6
 72
hr
 1235 3752 4156 0.9028 0.8617
MCF7 Alpelisib
0.12
uM
LJP5
 72
hr
 1235 3450 4156 0.8303 0.7585
MCF7 Luminespib
0.12
uM
LJP5
 72
hr
 1235 1413 4156 0.3401 0.0610
MCF7 A443654
0.12
uM
LJP6
 72
hr
 1235 982 4156 0.2364 -0.0865
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1235 3019 4156 0.7265 0.6108
MCF7 XMD11-85h
0.12
uM
LJP6
 72
hr
 1235 3496 4156 0.8412 0.7741
MCF7 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1235 4613 4156 1.1101 1.1566
MCF7 WH-4-025
0.12
uM
LJP5
 72
hr
 1235 2787 4156 0.6707 0.5315
MCF7 WZ-4-145
0.12
uM
LJP6
 72
hr
 1235 2859 4156 0.6881 0.5561
MCF7 XMD16-144
0.12
uM
LJP5
 72
hr
 1235 1640 4156 0.3946 0.1385
MCF7 Brivanib
0.12
uM
LJP5
 72
hr
 1235 3502 4156 0.8428 0.7763
MCF7 Buparlisib
0.12
uM
LJP5
 72
hr
 1235 2627 4156 0.6322 0.4767
MCF7 BX-912
0.12
uM
LJP5
 72
hr
 1235 3692 4156 0.8883 0.8411
MCF7 Canertinib
0.12
uM
LJP6
 72
hr
 1235 3572 4156 0.8595 0.8001
MCF7 Celastrol
0.12
uM
LJP6
 72
hr
 1235 3998 4156 0.9620 0.9460
MCF7 CGP60474
0.12
uM
LJP5
 72
hr
 1235 774 4156 0.1862 -0.1580
MCF7 CGP60474
0.12
uM
LJP6
 72
hr
 1235 587 4156 0.1413 -0.2219
MCF7 CHIR-99021
0.12
uM
LJP6
 72
hr
 1235 3240 4156 0.7796 0.6864
MCF7 CP724714
0.12
uM
LJP5
 72
hr
 1235 3363 4156 0.8092 0.7284
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1235 4537 4156 1.0918 1.1306
MCF7 Crizotinib
0.12
uM
LJP5
 72
hr
 1235 3061 4156 0.7367 0.6253
MCF7 Momelotinib
0.12
uM
LJP5
 72
hr
 1235 3478 4156 0.8368 0.7678
MCF7 Dasatinib
0.12
uM
LJP5
 72
hr
 1235 1273 4156 0.3065 0.0131