LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 72 | hr | 513 | 415 | 10401 | 0.0400 | -0.0099 |
| MCF 10A | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 513 | 838 | 10401 | 0.0806 | 0.0328 |
| MCF 10A | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 513 | 5283 | 10401 | 0.5080 | 0.4824 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 513 | 246 | 10401 | 0.0237 | -0.0270 |
| MCF 10A | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 513 | 882 | 10401 | 0.0849 | 0.0373 |
| MCF 10A | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 513 | 483 | 10401 | 0.0464 | -0.0031 |
| MCF 10A | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 513 | 649 | 10401 | 0.0624 | 0.0137 |
| MCF 10A | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 513 | 1479 | 10401 | 0.1423 | 0.0977 |
| MCF 10A | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 513 | 331 | 10401 | 0.0319 | -0.0184 |
| MCF 10A | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 513 | 957 | 10401 | 0.0920 | 0.0449 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 513 | 223 | 10401 | 0.0215 | -0.0293 |
| MCF 10A | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 513 | 525 | 10401 | 0.0505 | 0.0012 |
| MCF 10A | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 513 | 523 | 10401 | 0.0503 | 0.0010 |
| MCF 10A | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 513 | 402 | 10401 | 0.0387 | -0.0113 |
| MCF 10A | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 513 | 4632 | 10401 | 0.4453 | 0.4165 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 513 | 9029 | 10401 | 0.8681 | 0.8613 |
| MCF 10A | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 513 | 2844 | 10401 | 0.2734 | 0.2357 |
| MCF 10A | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 739 | 10401 | 0.0711 | 0.0229 |
| MCF 10A | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 1580 | 10401 | 0.1520 | 0.1079 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 332 | 10401 | 0.0320 | -0.0183 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 513 | 217 | 10401 | 0.0209 | -0.0300 |
| MCF 10A | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 652 | 10401 | 0.0627 | 0.0140 |
| MCF 10A | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 513 | 7625 | 10401 | 0.7332 | 0.7193 |
| MCF 10A | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 773 | 10401 | 0.0743 | 0.0263 |
| MCF 10A | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 463 | 10401 | 0.0445 | -0.0051 |