LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | R406 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2794 | 3486 | 0.8015 | 0.7357 |
| MDA-MB-231 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 868 | 2542 | 3486 | 0.7292 | 0.6394 |
| MDA-MB-231 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 868 | 3791 | 3486 | 1.0874 | 1.1163 |
| MDA-MB-231 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 868 | 1062 | 3486 | 0.3046 | 0.0740 |
| MDA-MB-231 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 868 | 1172 | 3486 | 0.3362 | 0.1161 |
| MDA-MB-231 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 868 | 1671 | 3486 | 0.4793 | 0.3066 |
| MDA-MB-231 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1919 | 3486 | 0.5506 | 0.4016 |
| MDA-MB-231 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 868 | 3232 | 3486 | 0.9270 | 0.9028 |
| MDA-MB-231 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 868 | 1044 | 3486 | 0.2996 | 0.0674 |
| MDA-MB-231 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 868 | 3209 | 3486 | 0.9205 | 0.8942 |
| MDA-MB-231 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 868 | 1052 | 3486 | 0.3019 | 0.0705 |
| MDA-MB-231 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 868 | 1673 | 3486 | 0.4801 | 0.3077 |
| MDA-MB-231 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2385 | 3486 | 0.6843 | 0.5796 |
| MDA-MB-231 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 868 | 3756 | 3486 | 1.0775 | 1.1032 |
| MDA-MB-231 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 868 | 1223 | 3486 | 0.3508 | 0.1355 |
| MDA-MB-231 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2065 | 3486 | 0.5925 | 0.4574 |
| MDA-MB-231 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 868 | 3474 | 3486 | 0.9964 | 0.9953 |
| MDA-MB-231 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2550 | 3486 | 0.7316 | 0.6426 |
| MDA-MB-231 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 868 | 3871 | 3486 | 1.1103 | 1.1469 |
| MDA-MB-231 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 868 | 2978 | 3486 | 0.8543 | 0.8060 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 868 | 718 | 3486 | 0.2059 | -0.0573 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 868 | 718 | 3486 | 0.2061 | -0.0571 |
| MDA-MB-231 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2676 | 3486 | 0.7678 | 0.6907 |
| MDA-MB-231 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 868 | 1904 | 3486 | 0.5461 | 0.3956 |
| MDA-MB-231 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 868 | 2314 | 3486 | 0.6638 | 0.5524 |