LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 72
hr
 868 331 3486 0.0949 -0.2051
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 72
hr
 868 290 3486 0.0832 -0.2208
MDA-MB-231 MK2206
10.0
uM
LJP6
 72
hr
 868 1139 3486 0.3268 0.1036
MDA-MB-231 Neratinib
10.0
uM
LJP5
 72
hr
 868 715 3486 0.2051 -0.0585
MDA-MB-231 Nilotinib
10.0
uM
LJP5
 72
hr
 868 1235 3486 0.3544 0.1404
MDA-MB-231 Nintedanib
10.0
uM
LJP6
 72
hr
 868 641 3486 0.1840 -0.0866
MDA-MB-231 NU7441
10.0
uM
LJP5
 72
hr
 868 1159 3486 0.3326 0.1114
MDA-MB-231 Dactolisib
10.0
uM
LJP5
 72
hr
 868 1555 3486 0.4460 0.2623
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 72
hr
 868 698 3486 0.2003 -0.0648
MDA-MB-231 Palbociclib
10.0
uM
LJP6
 72
hr
 868 1490 3486 0.4275 0.2376
MDA-MB-231 PD0325901
10.0
uM
LJP5
 72
hr
 868 898 3486 0.2576 0.0114
MDA-MB-231 PD0325901
10.0
uM
LJP6
 72
hr
 868 826 3486 0.2371 -0.0158
MDA-MB-231 PD173074
10.0
uM
LJP6
 72
hr
 868 1273 3486 0.3652 0.1548
MDA-MB-231 PD184352
10.0
uM
LJP5
 72
hr
 868 1359 3486 0.3900 0.1877
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 72
hr
 868 713 3486 0.2045 -0.0592
MDA-MB-231 PF431396
10.0
uM
LJP5
 72
hr
 868 882 3486 0.2530 0.0053
MDA-MB-231 PF477736
10.0
uM
LJP5
 72
hr
 868 1078 3486 0.3092 0.0802
MDA-MB-231 PF562271
10.0
uM
LJP6
 72
hr
 868 897 3486 0.2575 0.0113
MDA-MB-231 PHA-665752
10.0
uM
LJP5
 72
hr
 868 653 3486 0.1875 -0.0819
MDA-MB-231 PHA-793887
10.0
uM
LJP6
 72
hr
 868 751 3486 0.2155 -0.0446
MDA-MB-231 PI103
10.0
uM
LJP6
 72
hr
 868 1482 3486 0.4253 0.2347
MDA-MB-231 PLX-4720
10.0
uM
LJP5
 72
hr
 868 1683 3486 0.4828 0.3114
MDA-MB-231 QL-X-138
10.0
uM
LJP6
 72
hr
 868 849 3486 0.2436 -0.0072
MDA-MB-231 QL-XII-47
10.0
uM
LJP6
 72
hr
 868 810 3486 0.2323 -0.0222
MDA-MB-231 Radicicol
10.0
uM
LJP5
 72
hr
 868 1020 3486 0.2928 0.0583