LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 868 | 1066 | 3486 | 0.3058 | 0.0756 |
| MDA-MB-231 | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 868 | 1507 | 3486 | 0.4324 | 0.2441 |
| MDA-MB-231 | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 868 | 2760 | 3486 | 0.7918 | 0.7228 |
| MDA-MB-231 | XL147 | 10.0 | uM | LJP5 | 72 | hr | 868 | 3316 | 3486 | 0.9513 | 0.9352 |
| MDA-MB-231 | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 868 | 1895 | 3486 | 0.5437 | 0.3925 |
| MDA-MB-231 | Selumetinib | 10.0 | uM | LJP6 | 72 | hr | 868 | 1467 | 3486 | 0.4208 | 0.2287 |
| MDA-MB-231 | Sirolimus | 10.0 | uM | LJP6 | 72 | hr | 868 | 2997 | 3486 | 0.8596 | 0.8131 |
| MDA-MB-231 | Sorafenib | 10.0 | uM | LJP6 | 72 | hr | 868 | 2448 | 3486 | 0.7022 | 0.6034 |
| MDA-MB-231 | SU11274 | 10.0 | uM | LJP5 | 72 | hr | 868 | 1257 | 3486 | 0.3605 | 0.1485 |
| MDA-MB-231 | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 868 | 618 | 3486 | 0.1774 | -0.0954 |
| MDA-MB-231 | TGX221 | 10.0 | uM | LJP5 | 72 | hr | 868 | 2894 | 3486 | 0.8301 | 0.7738 |
| MDA-MB-231 | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 868 | 1017 | 3486 | 0.2918 | 0.0570 |
| MDA-MB-231 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 868 | 861 | 3486 | 0.2471 | -0.0026 |
| MDA-MB-231 | Tozasertib | 10.0 | uM | LJP5 | 72 | hr | 868 | 1349 | 3486 | 0.3870 | 0.1838 |
| MDA-MB-231 | Trametinib | 10.0 | uM | LJP5 | 72 | hr | 868 | 1306 | 3486 | 0.3746 | 0.1672 |
| MDA-MB-231 | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 868 | 866 | 3486 | 0.2486 | -0.0006 |
| MDA-MB-231 | Vemurafenib | 10.0 | uM | LJP5 | 72 | hr | 868 | 1762 | 3486 | 0.5054 | 0.3414 |
| MDA-MB-231 | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 868 | 476 | 3486 | 0.1365 | -0.1498 |
| MDA-MB-231 | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 868 | 532 | 3486 | 0.1527 | -0.1283 |
| MDA-MB-231 | WYE-125132 | 10.0 | uM | LJP6 | 72 | hr | 868 | 1386 | 3486 | 0.3976 | 0.1979 |
| MDA-MB-231 | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 868 | 838 | 3486 | 0.2404 | -0.0115 |
| MDA-MB-231 | XMD11-50 | 10.0 | uM | LJP6 | 72 | hr | 868 | 1306 | 3486 | 0.3747 | 0.1674 |
| MDA-MB-231 | Y39983 | 10.0 | uM | LJP6 | 72 | hr | 868 | 573 | 3486 | 0.1644 | -0.1127 |
| MDA-MB-231 | YM 201636 | 10.0 | uM | LJP5 | 72 | hr | 868 | 1597 | 3486 | 0.4583 | 0.2786 |
| MDA-MB-231 | ZSTK474 | 10.0 | uM | LJP6 | 72 | hr | 868 | 1948 | 3486 | 0.5589 | 0.4127 |