LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1512 | 4156 | 0.3639 | 0.0948 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2068 | 4156 | 0.4976 | 0.2851 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 565 | 4156 | 0.1361 | -0.2293 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1252 | 4156 | 0.3014 | 0.0059 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2156 | 4156 | 0.5188 | 0.3153 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4899 | 4156 | 1.1787 | 1.2543 |
| MCF7 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4643 | 4156 | 1.1173 | 1.1669 |
| MCF7 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3697 | 4156 | 0.8895 | 0.8428 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2254 | 4156 | 0.5424 | 0.3489 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1481 | 4156 | 0.3564 | 0.0842 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 790 | 4156 | 0.1901 | -0.1525 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1974 | 4156 | 0.4750 | 0.2529 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3439 | 4156 | 0.8275 | 0.7545 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3432 | 4156 | 0.8259 | 0.7523 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1226 | 4156 | 0.2950 | -0.0032 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2094 | 4156 | 0.5039 | 0.2941 |
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1787 | 4156 | 0.4300 | 0.1889 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3667 | 4156 | 0.8823 | 0.8325 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 935 | 4156 | 0.2251 | -0.1026 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2350 | 4156 | 0.5655 | 0.3817 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2787 | 4156 | 0.6707 | 0.5314 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1313 | 4156 | 0.3160 | 0.0267 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 861 | 4156 | 0.2073 | -0.1280 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 551 | 4156 | 0.1326 | -0.2343 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2455 | 4156 | 0.5908 | 0.4177 |