LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 TWS119
0.04
uM
LJP5
 72
hr
 1235 4758 4156 1.1449 1.2062
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4219 4156 1.0153 1.0217
MCF7 Withaferin A
0.04
uM
LJP5
 72
hr
 1235 4676 4156 1.1251 1.1780
MCF7 Withaferin A
0.04
uM
LJP6
 72
hr
 1235 3891 4156 0.9364 0.9094
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1235 1763 4156 0.4242 0.1806
MCF7 WZ3105
0.04
uM
LJP5
 72
hr
 1235 751 4156 0.1809 -0.1656
MCF7 XMD11-50
0.04
uM
LJP6
 72
hr
 1235 3637 4156 0.8752 0.8224
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1235 4249 4156 1.0223 1.0318
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4588 4156 1.1040 1.1480
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1235 3330 4156 0.8012 0.7171
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1235 2890 4156 0.6955 0.5667
MCF7 Sigma A6730
0.12
uM
LJP5
 72
hr
 1235 3215 4156 0.7736 0.6778
MCF7 Alvocidib
0.12
uM
LJP6
 72
hr
 1235 676 4156 0.1627 -0.1915
MCF7 AT-7519
0.12
uM
LJP6
 72
hr
 1235 1396 4156 0.3360 0.0551
MCF7 AZD 5438
0.12
uM
LJP6
 72
hr
 1235 2135 4156 0.5137 0.3080
MCF7 AZD-6482
0.12
uM
LJP5
 72
hr
 1235 3850 4156 0.9264 0.8953
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1235 1706 4156 0.4106 0.1612
MCF7 AZD8055
0.12
uM
LJP6
 72
hr
 1235 1319 4156 0.3174 0.0287
MCF7 AZD8330
0.12
uM
LJP5
 72
hr
 1235 1986 4156 0.4780 0.2572
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1235 1597 4156 0.3844 0.1240
MCF7 BI-2536
0.12
uM
LJP6
 72
hr
 1235 1399 4156 0.3368 0.0562
MCF7 BMS345541
0.12
uM
LJP6
 72
hr
 1235 4307 4156 1.0363 1.0516
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1235 632 4156 0.1522 -0.2064
MCF7 GDC-0980
0.12
uM
LJP5
 72
hr
 1235 1163 4156 0.2799 -0.0247
MCF7 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1235 3844 4156 0.9249 0.8931