LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 PF431396
0.04
uM
LJP5
 72
hr
 1235 3176 4156 0.7643 0.6646
MCF7 PF477736
0.04
uM
LJP5
 72
hr
 1235 2602 4156 0.6261 0.4680
MCF7 PF562271
0.04
uM
LJP6
 72
hr
 1235 3573 4156 0.8599 0.8006
MCF7 PHA-665752
0.04
uM
LJP5
 72
hr
 1235 4485 4156 1.0791 1.1126
MCF7 PHA-793887
0.04
uM
LJP6
 72
hr
 1235 1311 4156 0.3155 0.0260
MCF7 PI103
0.04
uM
LJP6
 72
hr
 1235 3469 4156 0.8348 0.7650
MCF7 PLX-4720
0.04
uM
LJP5
 72
hr
 1235 4683 4156 1.1269 1.1806
MCF7 QL-X-138
0.04
uM
LJP6
 72
hr
 1235 1814 4156 0.4366 0.1983
MCF7 QL-XII-47
0.04
uM
LJP6
 72
hr
 1235 2788 4156 0.6710 0.5318
MCF7 Radicicol
0.04
uM
LJP5
 72
hr
 1235 2719 4156 0.6544 0.5082
MCF7 Radicicol
0.04
uM
LJP6
 72
hr
 1235 2568 4156 0.6179 0.4563
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1235 4831 4156 1.1625 1.2313
MCF7 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1235 3891 4156 0.9363 0.9093
MCF7 XL147
0.04
uM
LJP5
 72
hr
 1235 4765 4156 1.1466 1.2086
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1235 3767 4156 0.9064 0.8669
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1235 3986 4156 0.9592 0.9420
MCF7 Sirolimus
0.04
uM
LJP6
 72
hr
 1235 2655 4156 0.6390 0.4863
MCF7 Sorafenib
0.04
uM
LJP6
 72
hr
 1235 3940 4156 0.9482 0.9262
MCF7 SU11274
0.04
uM
LJP5
 72
hr
 1235 4880 4156 1.1743 1.2481
MCF7 Fedratinib
0.04
uM
LJP5
 72
hr
 1235 4587 4156 1.1037 1.1475
MCF7 TGX221
0.04
uM
LJP5
 72
hr
 1235 3428 4156 0.8248 0.7507
MCF7 Torin1
0.04
uM
LJP6
 72
hr
 1235 1714 4156 0.4126 0.1641
MCF7 Torin2
0.04
uM
LJP5
 72
hr
 1235 1225 4156 0.2947 -0.0036
MCF7 Tozasertib
0.04
uM
LJP5
 72
hr
 1235 1440 4156 0.3465 0.0701
MCF7 Trametinib
0.04
uM
LJP5
 72
hr
 1235 2062 4156 0.4961 0.2830