LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4070 | 4156 | 0.9794 | 0.9707 |
| MCF7 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1398 | 4156 | 0.3364 | 0.0557 |
| MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1086 | 4156 | 0.2615 | -0.0509 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1483 | 4156 | 0.3569 | 0.0849 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2126 | 4156 | 0.5116 | 0.3050 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4026 | 4156 | 0.9687 | 0.9554 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4319 | 4156 | 1.0392 | 1.0557 |
| MCF7 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1871 | 4156 | 0.4503 | 0.2179 |
| MCF7 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1735 | 4156 | 0.4175 | 0.1712 |
| MCF7 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1641 | 4156 | 0.3950 | 0.1391 |
| MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 883 | 4156 | 0.2126 | -0.1204 |
| MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2730 | 4156 | 0.6569 | 0.5118 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 4011 | 4156 | 0.9652 | 0.9504 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 3881 | 4156 | 0.9339 | 0.9059 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1566 | 4156 | 0.3768 | 0.1132 |
| MCF7 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3186 | 4156 | 0.7667 | 0.6681 |
| MCF7 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2317 | 4156 | 0.5576 | 0.3704 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 573 | 4156 | 0.1379 | -0.2268 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 861 | 4156 | 0.2072 | -0.1281 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1192 | 4156 | 0.2868 | -0.0149 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4006 | 4156 | 0.9640 | 0.9487 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1310 | 4156 | 0.3153 | 0.0257 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1291 | 4156 | 0.3108 | 0.0193 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2392 | 4156 | 0.5755 | 0.3960 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1547 | 4156 | 0.3724 | 0.1069 |