LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3826 | 3694 | 1.0357 | 1.0595 |
| SK-BR-3 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1829 | 3694 | 0.4952 | 0.1590 |
| SK-BR-3 | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2550 | 3694 | 0.6903 | 0.4840 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1447 | 3694 | 0.3918 | -0.0133 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1309 | 3694 | 0.3544 | -0.0756 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2676 | 3694 | 0.7245 | 0.5410 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2285 | 3694 | 0.6187 | 0.3648 |
| SK-BR-3 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3597 | 3694 | 0.9737 | 0.9562 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1296 | 3694 | 0.3510 | -0.0812 |
| SK-BR-3 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2605 | 3694 | 0.7053 | 0.5090 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1355 | 3694 | 0.3670 | -0.0546 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1830 | 3694 | 0.4954 | 0.1593 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2878 | 3694 | 0.7793 | 0.6323 |
| SK-BR-3 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3744 | 3694 | 1.0137 | 1.0228 |
| SK-BR-3 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2457 | 3694 | 0.6652 | 0.4423 |
| SK-BR-3 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2648 | 3694 | 0.7170 | 0.5285 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1511 | 3694 | 0.4092 | 0.0158 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4182 | 3694 | 1.1322 | 1.2202 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3937 | 3694 | 1.0659 | 1.1097 |
| SK-BR-3 | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3099 | 3694 | 0.8389 | 0.7316 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1603 | 3694 | 0.4339 | 0.0570 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1556 | 3694 | 0.4213 | 0.0359 |
| SK-BR-3 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2557 | 3694 | 0.6923 | 0.4874 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1340 | 3694 | 0.3628 | -0.0615 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4087 | 3694 | 1.1065 | 1.1774 |