LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3575 | 3694 | 0.9680 | 0.9466 |
| SK-BR-3 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3321 | 3694 | 0.8992 | 0.8321 |
| SK-BR-3 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1629 | 3694 | 0.4412 | 0.0690 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3310 | 3694 | 0.8960 | 0.8268 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2860 | 3694 | 0.7744 | 0.6242 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3517 | 3694 | 0.9521 | 0.9202 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3550 | 3694 | 0.9611 | 0.9352 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 4062 | 3694 | 1.0997 | 1.1661 |
| SK-BR-3 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3824 | 3694 | 1.0352 | 1.0586 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1478 | 3694 | 0.4001 | 0.0006 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2147 | 3694 | 0.5814 | 0.3026 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1407 | 3694 | 0.3810 | -0.0313 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2980 | 3694 | 0.8067 | 0.6780 |
| SK-BR-3 | PHA-665752 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4197 | 3694 | 1.1362 | 1.2270 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1524 | 3694 | 0.4127 | 0.0215 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1954 | 3694 | 0.5291 | 0.2156 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4215 | 3694 | 1.1411 | 1.2351 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1877 | 3694 | 0.5081 | 0.1805 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1403 | 3694 | 0.3800 | -0.0329 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1683 | 3694 | 0.4557 | 0.0932 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1644 | 3694 | 0.4452 | 0.0757 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3951 | 3694 | 1.0696 | 1.1159 |
| SK-BR-3 | Ruxolitinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3362 | 3694 | 0.9102 | 0.8504 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4284 | 3694 | 1.1598 | 1.2662 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3815 | 3694 | 1.0327 | 1.0545 |