LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1476 | 998 | 3694 | 0.2703 | -0.2156 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1082 | 3694 | 0.2931 | -0.1777 |
| SK-BR-3 | MK2206 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2087 | 3694 | 0.5651 | 0.2754 |
| SK-BR-3 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1349 | 3694 | 0.3652 | -0.0576 |
| SK-BR-3 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3802 | 3694 | 1.0294 | 1.0490 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2580 | 3694 | 0.6986 | 0.4979 |
| SK-BR-3 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2677 | 3694 | 0.7247 | 0.5413 |
| SK-BR-3 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1444 | 3694 | 0.3909 | -0.0148 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1545 | 3694 | 0.4182 | 0.0308 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2765 | 3694 | 0.7487 | 0.5813 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2433 | 3694 | 0.6587 | 0.4314 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2351 | 3694 | 0.6366 | 0.3946 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 4220 | 3694 | 1.1424 | 1.2372 |
| SK-BR-3 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3597 | 3694 | 0.9738 | 0.9564 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1634 | 3694 | 0.4423 | 0.0709 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1433 | 3694 | 0.3880 | -0.0196 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1343 | 3694 | 0.3637 | -0.0602 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1361 | 3694 | 0.3685 | -0.0520 |
| SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3662 | 3694 | 0.9915 | 0.9859 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1437 | 3694 | 0.3892 | -0.0176 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1542 | 3694 | 0.4176 | 0.0297 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2775 | 3694 | 0.7513 | 0.5857 |
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1592 | 3694 | 0.4311 | 0.0521 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 931 | 3694 | 0.2520 | -0.2461 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1575 | 3694 | 0.4264 | 0.0443 |