LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | Sirolimus | 3.33 | uM | LJP6 | 3 | L14 | 72 | hr | 1235 | 3451 | 4513 | 0.7646 | 0.6758 |
MDA-MB-231 | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 1235 | 4425 | 4513 | 0.9804 | 0.9730 |
MDA-MB-231 | Sorafenib | 3.33 | uM | LJP6 | 2 | B08 | 72 | hr | 1235 | 4195 | 4513 | 0.9294 | 0.9028 |
MDA-MB-231 | Sorafenib | 3.33 | uM | LJP6 | 3 | B08 | 72 | hr | 1235 | 4873 | 4513 | 1.0796 | 1.1096 |
MDA-MB-231 | SU11274 | 3.33 | uM | LJP5 | 1 | J08 | 72 | hr | 1235 | 3441 | 4513 | 0.7624 | 0.6727 |
MDA-MB-231 | SU11274 | 3.33 | uM | LJP5 | 2 | J08 | 72 | hr | 1235 | 3585 | 4513 | 0.7943 | 0.7167 |
MDA-MB-231 | SU11274 | 3.33 | uM | LJP5 | 3 | J08 | 72 | hr | 1235 | 3992 | 4513 | 0.8844 | 0.8409 |
MDA-MB-231 | Fedratinib | 3.33 | uM | LJP5 | 1 | L02 | 72 | hr | 1235 | 1002 | 4513 | 0.2220 | -0.0714 |
MDA-MB-231 | Fedratinib | 3.33 | uM | LJP5 | 2 | L02 | 72 | hr | 1235 | 1146 | 4513 | 0.2539 | -0.0274 |
MDA-MB-231 | Fedratinib | 3.33 | uM | LJP5 | 3 | L02 | 72 | hr | 1235 | 1161 | 4513 | 0.2572 | -0.0229 |
MDA-MB-231 | TGX221 | 3.33 | uM | LJP5 | 1 | H20 | 72 | hr | 1235 | 3806 | 4513 | 0.8432 | 0.7841 |
MDA-MB-231 | TGX221 | 3.33 | uM | LJP5 | 2 | H20 | 72 | hr | 1235 | 4226 | 4513 | 0.9363 | 0.9122 |
MDA-MB-231 | TGX221 | 3.33 | uM | LJP5 | 3 | H20 | 72 | hr | 1235 | 4723 | 4513 | 1.0464 | 1.0639 |
MDA-MB-231 | Torin1 | 3.33 | uM | LJP6 | 1 | O14 | 72 | hr | 1235 | 1238 | 4513 | 0.2743 | 0.0006 |
MDA-MB-231 | Torin1 | 3.33 | uM | LJP6 | 2 | O14 | 72 | hr | 1235 | 1683 | 4513 | 0.3729 | 0.1364 |
MDA-MB-231 | Torin1 | 3.33 | uM | LJP6 | 3 | O14 | 72 | hr | 1235 | 1307 | 4513 | 0.2896 | 0.0217 |
MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 1 | I20 | 72 | hr | 1235 | 1 | 4513 | 0.0002 | -0.3768 |
MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 2 | I20 | 72 | hr | 1235 | 413 | 4513 | 0.0915 | -0.2511 |
MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 3 | I20 | 72 | hr | 1235 | 870 | 4513 | 0.1928 | -0.1117 |
MDA-MB-231 | Tozasertib | 3.33 | uM | LJP5 | 1 | B14 | 72 | hr | 1235 | 1408 | 4513 | 0.3119 | 0.0525 |
MDA-MB-231 | Tozasertib | 3.33 | uM | LJP5 | 2 | B14 | 72 | hr | 1235 | 1557 | 4513 | 0.3450 | 0.0979 |
MDA-MB-231 | Tozasertib | 3.33 | uM | LJP5 | 3 | B14 | 72 | hr | 1235 | 1298 | 4513 | 0.2876 | 0.0189 |
MDA-MB-231 | Trametinib | 3.33 | uM | LJP5 | 1 | P20 | 72 | hr | 1235 | 1210 | 4513 | 0.2681 | -0.0079 |
MDA-MB-231 | Trametinib | 3.33 | uM | LJP5 | 2 | P20 | 72 | hr | 1235 | 1270 | 4513 | 0.2814 | 0.0104 |
MDA-MB-231 | Trametinib | 3.33 | uM | LJP5 | 3 | P20 | 72 | hr | 1235 | 1347 | 4513 | 0.2984 | 0.0339 |