LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Sirolimus
3.33
uM
LJP6
3
L14
72
hr
1235 3451 4513 0.7646 0.6758
MDA-MB-231 Sorafenib
3.33
uM
LJP6
1
B08
72
hr
1235 4425 4513 0.9804 0.9730
MDA-MB-231 Sorafenib
3.33
uM
LJP6
2
B08
72
hr
1235 4195 4513 0.9294 0.9028
MDA-MB-231 Sorafenib
3.33
uM
LJP6
3
B08
72
hr
1235 4873 4513 1.0796 1.1096
MDA-MB-231 SU11274
3.33
uM
LJP5
1
J08
72
hr
1235 3441 4513 0.7624 0.6727
MDA-MB-231 SU11274
3.33
uM
LJP5
2
J08
72
hr
1235 3585 4513 0.7943 0.7167
MDA-MB-231 SU11274
3.33
uM
LJP5
3
J08
72
hr
1235 3992 4513 0.8844 0.8409
MDA-MB-231 Fedratinib
3.33
uM
LJP5
1
L02
72
hr
1235 1002 4513 0.2220 -0.0714
MDA-MB-231 Fedratinib
3.33
uM
LJP5
2
L02
72
hr
1235 1146 4513 0.2539 -0.0274
MDA-MB-231 Fedratinib
3.33
uM
LJP5
3
L02
72
hr
1235 1161 4513 0.2572 -0.0229
MDA-MB-231 TGX221
3.33
uM
LJP5
1
H20
72
hr
1235 3806 4513 0.8432 0.7841
MDA-MB-231 TGX221
3.33
uM
LJP5
2
H20
72
hr
1235 4226 4513 0.9363 0.9122
MDA-MB-231 TGX221
3.33
uM
LJP5
3
H20
72
hr
1235 4723 4513 1.0464 1.0639
MDA-MB-231 Torin1
3.33
uM
LJP6
1
O14
72
hr
1235 1238 4513 0.2743 0.0006
MDA-MB-231 Torin1
3.33
uM
LJP6
2
O14
72
hr
1235 1683 4513 0.3729 0.1364
MDA-MB-231 Torin1
3.33
uM
LJP6
3
O14
72
hr
1235 1307 4513 0.2896 0.0217
MDA-MB-231 Torin2
3.33
uM
LJP5
1
I20
72
hr
1235 1 4513 0.0002 -0.3768
MDA-MB-231 Torin2
3.33
uM
LJP5
2
I20
72
hr
1235 413 4513 0.0915 -0.2511
MDA-MB-231 Torin2
3.33
uM
LJP5
3
I20
72
hr
1235 870 4513 0.1928 -0.1117
MDA-MB-231 Tozasertib
3.33
uM
LJP5
1
B14
72
hr
1235 1408 4513 0.3119 0.0525
MDA-MB-231 Tozasertib
3.33
uM
LJP5
2
B14
72
hr
1235 1557 4513 0.3450 0.0979
MDA-MB-231 Tozasertib
3.33
uM
LJP5
3
B14
72
hr
1235 1298 4513 0.2876 0.0189
MDA-MB-231 Trametinib
3.33
uM
LJP5
1
P20
72
hr
1235 1210 4513 0.2681 -0.0079
MDA-MB-231 Trametinib
3.33
uM
LJP5
2
P20
72
hr
1235 1270 4513 0.2814 0.0104
MDA-MB-231 Trametinib
3.33
uM
LJP5
3
P20
72
hr
1235 1347 4513 0.2984 0.0339