LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 GDC-0980
3.33
uM
LJP5
2
K20
72
hr
1235 1449 4513 0.3210 0.0650
MDA-MB-231 GDC-0980
3.33
uM
LJP5
3
K20
72
hr
1235 1771 4513 0.3924 0.1632
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
1
E14
72
hr
1235 4211 4513 0.9330 0.9077
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
2
E14
72
hr
1235 4585 4513 1.0158 1.0218
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
3
E14
72
hr
1235 4672 4513 1.0351 1.0483
MDA-MB-231 SB590885
3.33
uM
LJP5
1
L14
72
hr
1235 3487 4513 0.7726 0.6868
MDA-MB-231 SB590885
3.33
uM
LJP5
2
L14
72
hr
1235 3690 4513 0.8175 0.7487
MDA-MB-231 SB590885
3.33
uM
LJP5
3
L14
72
hr
1235 4242 4513 0.9398 0.9171
MDA-MB-231 PIK-93
3.33
uM
LJP5
1
K14
72
hr
1235 3599 4513 0.7974 0.7210
MDA-MB-231 PIK-93
3.33
uM
LJP5
2
K14
72
hr
1235 3715 4513 0.8231 0.7563
MDA-MB-231 PIK-93
3.33
uM
LJP5
3
K14
72
hr
1235 4287 4513 0.9498 0.9309
MDA-MB-231 KIN001-043
3.33
uM
LJP6
1
C08
72
hr
1235 3335 4513 0.7389 0.6404
MDA-MB-231 KIN001-043
3.33
uM
LJP6
2
C08
72
hr
1235 3146 4513 0.6970 0.5827
MDA-MB-231 KIN001-043
3.33
uM
LJP6
3
C08
72
hr
1235 3583 4513 0.7938 0.7161
MDA-MB-231 Alpelisib
3.33
uM
LJP5
1
N02
72
hr
1235 4080 4513 0.9039 0.8677
MDA-MB-231 Alpelisib
3.33
uM
LJP5
2
N02
72
hr
1235 3980 4513 0.8818 0.8372
MDA-MB-231 Alpelisib
3.33
uM
LJP5
3
N02
72
hr
1235 4687 4513 1.0384 1.0529
MDA-MB-231 Luminespib
3.33
uM
LJP5
1
H14
72
hr
1235 743 4513 0.1646 -0.1504
MDA-MB-231 Luminespib
3.33
uM
LJP5
2
H14
72
hr
1235 853 4513 0.1890 -0.1168
MDA-MB-231 Luminespib
3.33
uM
LJP5
3
H14
72
hr
1235 792 4513 0.1755 -0.1355
MDA-MB-231 A443654
3.33
uM
LJP6
1
I20
72
hr
1235 392 4513 0.0868 -0.2575
MDA-MB-231 A443654
3.33
uM
LJP6
2
I20
72
hr
1235 415 4513 0.0919 -0.2505
MDA-MB-231 A443654
3.33
uM
LJP6
3
I20
72
hr
1235 435 4513 0.0964 -0.2444
MDA-MB-231 OSI-027
3.33
uM
LJP6
1
E08
72
hr
1235 2527 4513 0.5599 0.3939
MDA-MB-231 OSI-027
3.33
uM
LJP6
2
E08
72
hr
1235 2862 4513 0.6341 0.4961