LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | GDC-0980 | 3.33 | uM | LJP5 | 2 | K20 | 72 | hr | 1235 | 1449 | 4513 | 0.3210 | 0.0650 |
MDA-MB-231 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1235 | 1771 | 4513 | 0.3924 | 0.1632 |
MDA-MB-231 | NVP-AEW541 | 3.33 | uM | LJP5 | 1 | E14 | 72 | hr | 1235 | 4211 | 4513 | 0.9330 | 0.9077 |
MDA-MB-231 | NVP-AEW541 | 3.33 | uM | LJP5 | 2 | E14 | 72 | hr | 1235 | 4585 | 4513 | 1.0158 | 1.0218 |
MDA-MB-231 | NVP-AEW541 | 3.33 | uM | LJP5 | 3 | E14 | 72 | hr | 1235 | 4672 | 4513 | 1.0351 | 1.0483 |
MDA-MB-231 | SB590885 | 3.33 | uM | LJP5 | 1 | L14 | 72 | hr | 1235 | 3487 | 4513 | 0.7726 | 0.6868 |
MDA-MB-231 | SB590885 | 3.33 | uM | LJP5 | 2 | L14 | 72 | hr | 1235 | 3690 | 4513 | 0.8175 | 0.7487 |
MDA-MB-231 | SB590885 | 3.33 | uM | LJP5 | 3 | L14 | 72 | hr | 1235 | 4242 | 4513 | 0.9398 | 0.9171 |
MDA-MB-231 | PIK-93 | 3.33 | uM | LJP5 | 1 | K14 | 72 | hr | 1235 | 3599 | 4513 | 0.7974 | 0.7210 |
MDA-MB-231 | PIK-93 | 3.33 | uM | LJP5 | 2 | K14 | 72 | hr | 1235 | 3715 | 4513 | 0.8231 | 0.7563 |
MDA-MB-231 | PIK-93 | 3.33 | uM | LJP5 | 3 | K14 | 72 | hr | 1235 | 4287 | 4513 | 0.9498 | 0.9309 |
MDA-MB-231 | KIN001-043 | 3.33 | uM | LJP6 | 1 | C08 | 72 | hr | 1235 | 3335 | 4513 | 0.7389 | 0.6404 |
MDA-MB-231 | KIN001-043 | 3.33 | uM | LJP6 | 2 | C08 | 72 | hr | 1235 | 3146 | 4513 | 0.6970 | 0.5827 |
MDA-MB-231 | KIN001-043 | 3.33 | uM | LJP6 | 3 | C08 | 72 | hr | 1235 | 3583 | 4513 | 0.7938 | 0.7161 |
MDA-MB-231 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1235 | 4080 | 4513 | 0.9039 | 0.8677 |
MDA-MB-231 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 1235 | 3980 | 4513 | 0.8818 | 0.8372 |
MDA-MB-231 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1235 | 4687 | 4513 | 1.0384 | 1.0529 |
MDA-MB-231 | Luminespib | 3.33 | uM | LJP5 | 1 | H14 | 72 | hr | 1235 | 743 | 4513 | 0.1646 | -0.1504 |
MDA-MB-231 | Luminespib | 3.33 | uM | LJP5 | 2 | H14 | 72 | hr | 1235 | 853 | 4513 | 0.1890 | -0.1168 |
MDA-MB-231 | Luminespib | 3.33 | uM | LJP5 | 3 | H14 | 72 | hr | 1235 | 792 | 4513 | 0.1755 | -0.1355 |
MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 1 | I20 | 72 | hr | 1235 | 392 | 4513 | 0.0868 | -0.2575 |
MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 2 | I20 | 72 | hr | 1235 | 415 | 4513 | 0.0919 | -0.2505 |
MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 3 | I20 | 72 | hr | 1235 | 435 | 4513 | 0.0964 | -0.2444 |
MDA-MB-231 | OSI-027 | 3.33 | uM | LJP6 | 1 | E08 | 72 | hr | 1235 | 2527 | 4513 | 0.5599 | 0.3939 |
MDA-MB-231 | OSI-027 | 3.33 | uM | LJP6 | 2 | E08 | 72 | hr | 1235 | 2862 | 4513 | 0.6341 | 0.4961 |