LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | TWS119 | 3.33 | uM | LJP5 | 1 | M02 | 72 | hr | 1235 | 3064 | 4513 | 0.6788 | 0.5577 |
MDA-MB-231 | TWS119 | 3.33 | uM | LJP5 | 2 | M02 | 72 | hr | 1235 | 2752 | 4513 | 0.6097 | 0.4625 |
MDA-MB-231 | TWS119 | 3.33 | uM | LJP5 | 3 | M02 | 72 | hr | 1235 | 3306 | 4513 | 0.7325 | 0.6316 |
MDA-MB-231 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 1235 | 4115 | 4513 | 0.9117 | 0.8784 |
MDA-MB-231 | Vemurafenib | 3.33 | uM | LJP5 | 2 | C14 | 72 | hr | 1235 | 4115 | 4513 | 0.9117 | 0.8784 |
MDA-MB-231 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 1235 | 4444 | 4513 | 0.9846 | 0.9788 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP5 | 1 | G14 | 72 | hr | 1235 | 781 | 4513 | 0.1730 | -0.1388 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP5 | 2 | G14 | 72 | hr | 1235 | 914 | 4513 | 0.2025 | -0.0982 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP5 | 3 | G14 | 72 | hr | 1235 | 881 | 4513 | 0.1952 | -0.1083 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP6 | 1 | G14 | 72 | hr | 1235 | 767 | 4513 | 0.1699 | -0.1431 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP6 | 2 | G14 | 72 | hr | 1235 | 1165 | 4513 | 0.2581 | -0.0216 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP6 | 3 | G14 | 72 | hr | 1235 | 762 | 4513 | 0.1688 | -0.1446 |
MDA-MB-231 | WYE-125132 | 3.33 | uM | LJP6 | 1 | L08 | 72 | hr | 1235 | 1571 | 4513 | 0.3481 | 0.1022 |
MDA-MB-231 | WYE-125132 | 3.33 | uM | LJP6 | 2 | L08 | 72 | hr | 1235 | 1544 | 4513 | 0.3421 | 0.0940 |
MDA-MB-231 | WYE-125132 | 3.33 | uM | LJP6 | 3 | L08 | 72 | hr | 1235 | 1541 | 4513 | 0.3414 | 0.0931 |
MDA-MB-231 | WZ3105 | 3.33 | uM | LJP5 | 1 | D20 | 72 | hr | 1235 | 521 | 4513 | 0.1154 | -0.2181 |
MDA-MB-231 | WZ3105 | 3.33 | uM | LJP5 | 2 | D20 | 72 | hr | 1235 | 493 | 4513 | 0.1092 | -0.2267 |
MDA-MB-231 | WZ3105 | 3.33 | uM | LJP5 | 3 | D20 | 72 | hr | 1235 | 541 | 4513 | 0.1199 | -0.2120 |
MDA-MB-231 | XMD11-50 | 3.33 | uM | LJP6 | 1 | P08 | 72 | hr | 1235 | 1674 | 4513 | 0.3709 | 0.1337 |
MDA-MB-231 | XMD11-50 | 3.33 | uM | LJP6 | 2 | P08 | 72 | hr | 1235 | 1548 | 4513 | 0.3430 | 0.0952 |
MDA-MB-231 | XMD11-50 | 3.33 | uM | LJP6 | 3 | P08 | 72 | hr | 1235 | 1628 | 4513 | 0.3607 | 0.1196 |
MDA-MB-231 | Y39983 | 3.33 | uM | LJP6 | 1 | P02 | 72 | hr | 1235 | 2593 | 4513 | 0.5745 | 0.4140 |
MDA-MB-231 | Y39983 | 3.33 | uM | LJP6 | 2 | P02 | 72 | hr | 1235 | 2889 | 4513 | 0.6401 | 0.5043 |
MDA-MB-231 | Y39983 | 3.33 | uM | LJP6 | 3 | P02 | 72 | hr | 1235 | 3067 | 4513 | 0.6795 | 0.5586 |
MDA-MB-231 | YM 201636 | 3.33 | uM | LJP5 | 1 | N08 | 72 | hr | 1235 | 2380 | 4513 | 0.5273 | 0.3490 |