LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 2
O20
 72
hr
 1235 1038 4513 0.2300 -0.0604
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 3
O20
 72
hr
 1235 998 4513 0.2211 -0.0726
MDA-MB-231 Radicicol
3.33
uM
LJP5
 1
K08
 72
hr
 1235 839 4513 0.1859 -0.1211
MDA-MB-231 Radicicol
3.33
uM
LJP5
 2
K08
 72
hr
 1235 920 4513 0.2038 -0.0964
MDA-MB-231 Radicicol
3.33
uM
LJP5
 3
K08
 72
hr
 1235 991 4513 0.2196 -0.0747
MDA-MB-231 Radicicol
3.33
uM
LJP6
 1
K08
 72
hr
 1235 1062 4513 0.2353 -0.0531
MDA-MB-231 Radicicol
3.33
uM
LJP6
 2
K08
 72
hr
 1235 1160 4513 0.2570 -0.0232
MDA-MB-231 Radicicol
3.33
uM
LJP6
 3
K08
 72
hr
 1235 994 4513 0.2202 -0.0738
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 1235 3463 4513 0.7672 0.6795
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 1235 3698 4513 0.8193 0.7512
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 1235 4103 4513 0.9090 0.8747
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 1235 3970 4513 0.8796 0.8341
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 1235 4037 4513 0.8944 0.8546
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 1235 4719 4513 1.0455 1.0627
MDA-MB-231 XL147
3.33
uM
LJP5
 1
G08
 72
hr
 1235 4570 4513 1.0125 1.0172
MDA-MB-231 XL147
3.33
uM
LJP5
 2
G08
 72
hr
 1235 5042 4513 1.1171 1.1612
MDA-MB-231 XL147
3.33
uM
LJP5
 3
G08
 72
hr
 1235 4806 4513 1.0648 1.0892
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1235 2570 4513 0.5694 0.4070
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1235 2428 4513 0.5379 0.3637
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1235 2882 4513 0.6385 0.5022
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 1235 2269 4513 0.5027 0.3152
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 1235 2338 4513 0.5180 0.3362
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 1235 2389 4513 0.5293 0.3518
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 1235 3306 4513 0.7325 0.6316
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 1235 3177 4513 0.7039 0.5922