LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 3
M10
 72
hr
 868 1237 3486 0.3548 0.1409
MDA-MB-231 Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 868 2793 3486 0.8011 0.7352
MDA-MB-231 Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 868 3232 3486 0.9270 0.9028
MDA-MB-231 Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 868 2878 3486 0.8255 0.7676
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 868 2633 3486 0.7552 0.6741
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 868 2776 3486 0.7962 0.7287
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 868 2964 3486 0.8502 0.8005
MDA-MB-231 BX-912
0.37
uM
LJP5
 1
L22
 72
hr
 868 2730 3486 0.7830 0.7111
MDA-MB-231 BX-912
0.37
uM
LJP5
 2
L22
 72
hr
 868 3081 3486 0.8837 0.8452
MDA-MB-231 BX-912
0.37
uM
LJP5
 3
L22
 72
hr
 868 3070 3486 0.8806 0.8410
MDA-MB-231 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 868 2923 3486 0.8384 0.7848
MDA-MB-231 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 868 3358 3486 0.9632 0.9510
MDA-MB-231 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 868 3206 3486 0.9196 0.8929
MDA-MB-231 Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 868 2101 3486 0.6026 0.4709
MDA-MB-231 Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 868 1963 3486 0.5631 0.4182
MDA-MB-231 Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 868 1952 3486 0.5599 0.4140
MDA-MB-231 CGP60474
0.37
uM
LJP5
 1
F04
 72
hr
 868 717 3486 0.2057 -0.0577
MDA-MB-231 CGP60474
0.37
uM
LJP5
 2
F04
 72
hr
 868 622 3486 0.1784 -0.0940
MDA-MB-231 CGP60474
0.37
uM
LJP5
 3
F04
 72
hr
 868 748 3486 0.2146 -0.0459
MDA-MB-231 CGP60474
0.37
uM
LJP6
 1
G04
 72
hr
 868 824 3486 0.2364 -0.0169
MDA-MB-231 CGP60474
0.37
uM
LJP6
 2
G04
 72
hr
 868 835 3486 0.2395 -0.0126
MDA-MB-231 CGP60474
0.37
uM
LJP6
 3
G04
 72
hr
 868 765 3486 0.2194 -0.0394
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 868 2708 3486 0.7767 0.7027
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 868 2942 3486 0.8439 0.7921
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 868 3091 3486 0.8866 0.8490