LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 868 3673 3486 1.0535 1.0713
MDA-MB-231 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 868 3746 3486 1.0745 1.0992
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 868 2575 3486 0.7386 0.6519
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 868 2562 3486 0.7349 0.6469
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 868 2261 3486 0.6485 0.5320
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 1
B23
 72
hr
 868 2989 3486 0.8573 0.8100
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 2
B23
 72
hr
 868 2541 3486 0.7288 0.6389
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 3
B23
 72
hr
 868 2662 3486 0.7635 0.6851
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 868 3325 3486 0.9537 0.9384
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 868 3381 3486 0.9698 0.9598
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 868 3276 3486 0.9397 0.9196
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 1
G05
 72
hr
 868 3489 3486 1.0007 1.0010
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 2
G05
 72
hr
 868 3658 3486 1.0492 1.0655
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 3
G05
 72
hr
 868 3428 3486 0.9833 0.9777
MDA-MB-231 Linifanib
0.12
uM
LJP6
 1
J11
 72
hr
 868 3953 3486 1.1338 1.1782
MDA-MB-231 Linifanib
0.12
uM
LJP6
 2
J11
 72
hr
 868 3845 3486 1.1029 1.1370
MDA-MB-231 Linifanib
0.12
uM
LJP6
 3
J11
 72
hr
 868 4210 3486 1.2076 1.2764
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 868 2536 3486 0.7274 0.6370
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 868 2840 3486 0.8146 0.7531
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 868 2889 3486 0.8287 0.7718
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 868 932 3486 0.2673 0.0244
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 868 904 3486 0.2593 0.0137
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 868 948 3486 0.2719 0.0305
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 868 889 3486 0.2550 0.0080
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 868 910 3486 0.2610 0.0160