LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 868 2548 3486 0.7308 0.6416
MDA-MB-231 CP724714
0.37
uM
LJP5
 2
A10
 72
hr
 868 2567 3486 0.7363 0.6489
MDA-MB-231 CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 868 2816 3486 0.8077 0.7440
MDA-MB-231 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 868 3382 3486 0.9701 0.9601
MDA-MB-231 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 868 3561 3486 1.0214 1.0285
MDA-MB-231 CP466722
0.37
uM
LJP5
 3
I10
 72
hr
 868 3585 3486 1.0283 1.0377
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 868 2318 3486 0.6649 0.5538
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 868 2372 3486 0.6804 0.5744
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 868 2510 3486 0.7199 0.6271
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 868 2477 3486 0.7105 0.6145
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 868 2703 3486 0.7753 0.7008
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 868 2590 3486 0.7429 0.6576
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 868 517 3486 0.1483 -0.1341
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 868 521 3486 0.1494 -0.1326
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 868 451 3486 0.1294 -0.1593
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 868 583 3486 0.1672 -0.1089
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 868 568 3486 0.1629 -0.1146
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 868 484 3486 0.1388 -0.1467
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 868 1769 3486 0.5074 0.3441
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 868 2044 3486 0.5863 0.4491
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 868 1861 3486 0.5338 0.3792
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 868 3563 3486 1.0220 1.0293
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 868 3208 3486 0.9202 0.8937
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 868 3656 3486 1.0486 1.0648
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 868 3017 3486 0.8654 0.8207