LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 868 3690 3486 1.0584 1.0778
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 868 3393 3486 0.9732 0.9643
MDA-MB-231 Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 868 1150 3486 0.3299 0.1077
MDA-MB-231 Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 868 1043 3486 0.2992 0.0668
MDA-MB-231 Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 868 1008 3486 0.2891 0.0534
MDA-MB-231 A443654
0.37
uM
LJP6
 1
I22
 72
hr
 868 885 3486 0.2538 0.0064
MDA-MB-231 A443654
0.37
uM
LJP6
 2
I22
 72
hr
 868 879 3486 0.2521 0.0042
MDA-MB-231 A443654
0.37
uM
LJP6
 3
I22
 72
hr
 868 813 3486 0.2332 -0.0211
MDA-MB-231 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 868 3012 3486 0.8639 0.8188
MDA-MB-231 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 868 2491 3486 0.7145 0.6198
MDA-MB-231 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 868 3003 3486 0.8614 0.8154
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 1
P22
 72
hr
 868 2880 3486 0.8261 0.7684
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 2
P22
 72
hr
 868 2840 3486 0.8146 0.7531
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 3
P22
 72
hr
 868 2731 3486 0.7833 0.7115
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 1
M04
 72
hr
 868 2737 3486 0.7851 0.7138
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 2
M04
 72
hr
 868 2736 3486 0.7848 0.7134
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 3
M04
 72
hr
 868 2792 3486 0.8008 0.7348
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 868 1246 3486 0.3574 0.1443
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 868 1403 3486 0.4024 0.2043
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 868 1386 3486 0.3976 0.1978
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 1
J22
 72
hr
 868 2914 3486 0.8358 0.7814
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 2
J22
 72
hr
 868 3013 3486 0.8642 0.8192
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 3
J22
 72
hr
 868 2828 3486 0.8112 0.7485
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 1
M10
 72
hr
 868 1162 3486 0.3333 0.1122
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 2
M10
 72
hr
 868 1275 3486 0.3657 0.1554