LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Linifanib
3.33
uM
LJP6
 2
J08
 72
hr
 868 3977 3486 1.1407 1.1874
MDA-MB-231 Linifanib
3.33
uM
LJP6
 3
J08
 72
hr
 868 3978 3486 1.1410 1.1878
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 868 2570 3486 0.7372 0.6500
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 868 2947 3486 0.8453 0.7940
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 868 2700 3486 0.7744 0.6997
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 868 698 3486 0.2002 -0.0650
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 868 676 3486 0.1939 -0.0734
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 868 631 3486 0.1810 -0.0906
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 868 603 3486 0.1730 -0.1013
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 868 685 3486 0.1965 -0.0699
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 868 648 3486 0.1859 -0.0841
MDA-MB-231 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 868 2377 3486 0.6818 0.5763
MDA-MB-231 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 868 2801 3486 0.8034 0.7382
MDA-MB-231 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 868 2578 3486 0.7395 0.6531
MDA-MB-231 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 868 1446 3486 0.4148 0.2207
MDA-MB-231 Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 868 1403 3486 0.4024 0.2043
MDA-MB-231 Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 868 1841 3486 0.5281 0.3716
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 868 2179 3486 0.6250 0.5007
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 868 2613 3486 0.7495 0.6664
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 868 2338 3486 0.6706 0.5614
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 868 2215 3486 0.6353 0.5144
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 868 2590 3486 0.7429 0.6576
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 868 2661 3486 0.7633 0.6848
MDA-MB-231 NU7441
3.33
uM
LJP5
 1
C08
 72
hr
 868 2124 3486 0.6092 0.4797
MDA-MB-231 NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 868 2017 3486 0.5785 0.4388