LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 868 1755 3486 0.5034 0.3387
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 868 1888 3486 0.5415 0.3895
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 868 1795 3486 0.5149 0.3540
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 868 2591 3486 0.7432 0.6580
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 868 2811 3486 0.8063 0.7421
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 868 2741 3486 0.7862 0.7153
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 868 2550 3486 0.7314 0.6424
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 868 2694 3486 0.7727 0.6974
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 868 2676 3486 0.7676 0.6905
MDA-MB-231 SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 868 3194 3486 0.9161 0.8883
MDA-MB-231 SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 868 3582 3486 1.0274 1.0365
MDA-MB-231 SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 868 3406 3486 0.9769 0.9693
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 868 2134 3486 0.6121 0.4835
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 868 2230 3486 0.6396 0.5201
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 868 2417 3486 0.6933 0.5916
MDA-MB-231 TGX221
1.11
uM
LJP5
 1
H21
 72
hr
 868 2884 3486 0.8272 0.7699
MDA-MB-231 TGX221
1.11
uM
LJP5
 2
H21
 72
hr
 868 2973 3486 0.8527 0.8039
MDA-MB-231 TGX221
1.11
uM
LJP5
 3
H21
 72
hr
 868 2900 3486 0.8318 0.7760
MDA-MB-231 Torin1
1.11
uM
LJP6
 1
O15
 72
hr
 868 1363 3486 0.3910 0.1890
MDA-MB-231 Torin1
1.11
uM
LJP6
 2
O15
 72
hr
 868 1313 3486 0.3766 0.1699
MDA-MB-231 Torin1
1.11
uM
LJP6
 3
O15
 72
hr
 868 1293 3486 0.3709 0.1623
MDA-MB-231 Torin2
1.11
uM
LJP5
 1
I21
 72
hr
 868 966 3486 0.2771 0.0374
MDA-MB-231 Torin2
1.11
uM
LJP5
 2
I21
 72
hr
 868 1003 3486 0.2877 0.0515
MDA-MB-231 Torin2
1.11
uM
LJP5
 3
I21
 72
hr
 868 1145 3486 0.3284 0.1058
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 868 1064 3486 0.3052 0.0748