LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 868 1795 3486 0.5149 0.3540
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 868 1439 3486 0.4128 0.2180
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 868 1432 3486 0.4107 0.2154
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 868 1566 3486 0.4492 0.2665
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 868 1355 3486 0.3887 0.1860
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 868 1517 3486 0.4351 0.2478
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 868 1387 3486 0.3978 0.1982
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 868 1651 3486 0.4736 0.2990
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 868 1411 3486 0.4047 0.2073
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 868 1690 3486 0.4847 0.3139
MDA-MB-231 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 868 786 3486 0.2255 -0.0314
MDA-MB-231 PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 868 907 3486 0.2602 0.0149
MDA-MB-231 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 868 1130 3486 0.3241 0.1000
MDA-MB-231 PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 868 787 3486 0.2257 -0.0310
MDA-MB-231 PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 868 838 3486 0.2404 -0.0115
MDA-MB-231 PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 868 960 3486 0.2754 0.0351
MDA-MB-231 PD173074
3.33
uM
LJP6
 1
I08
 72
hr
 868 3544 3486 1.0165 1.0220
MDA-MB-231 PD173074
3.33
uM
LJP6
 2
I08
 72
hr
 868 3642 3486 1.0446 1.0594
MDA-MB-231 PD173074
3.33
uM
LJP6
 3
I08
 72
hr
 868 3770 3486 1.0813 1.1083
MDA-MB-231 PD184352
3.33
uM
LJP5
 1
L08
 72
hr
 868 1704 3486 0.4888 0.3193
MDA-MB-231 PD184352
3.33
uM
LJP5
 2
L08
 72
hr
 868 1889 3486 0.5418 0.3899
MDA-MB-231 PD184352
3.33
uM
LJP5
 3
L08
 72
hr
 868 1992 3486 0.5714 0.4292
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 868 1535 3486 0.4403 0.2547
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 868 1655 3486 0.4747 0.3005
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 868 1416 3486 0.4062 0.2093