LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Celastrol
10.0
uM
LJP6
 3
G07
 72
hr
 868 417 3486 0.1196 -0.1723
MDA-MB-231 CGP60474
10.0
uM
LJP5
 1
F01
 72
hr
 868 566 3486 0.1624 -0.1154
MDA-MB-231 CGP60474
10.0
uM
LJP5
 2
F01
 72
hr
 868 593 3486 0.1701 -0.1051
MDA-MB-231 CGP60474
10.0
uM
LJP5
 3
F01
 72
hr
 868 601 3486 0.1724 -0.1020
MDA-MB-231 CGP60474
10.0
uM
LJP6
 1
G01
 72
hr
 868 366 3486 0.1050 -0.1918
MDA-MB-231 CGP60474
10.0
uM
LJP6
 2
G01
 72
hr
 868 456 3486 0.1308 -0.1574
MDA-MB-231 CGP60474
10.0
uM
LJP6
 3
G01
 72
hr
 868 585 3486 0.1678 -0.1081
MDA-MB-231 CHIR-99021
10.0
uM
LJP6
 1
P13
 72
hr
 868 2628 3486 0.7538 0.6722
MDA-MB-231 CHIR-99021
10.0
uM
LJP6
 2
P13
 72
hr
 868 3129 3486 0.8975 0.8635
MDA-MB-231 CHIR-99021
10.0
uM
LJP6
 3
P13
 72
hr
 868 2843 3486 0.8155 0.7543
MDA-MB-231 CP724714
10.0
uM
LJP5
 1
A07
 72
hr
 868 2441 3486 0.7002 0.6007
MDA-MB-231 CP724714
10.0
uM
LJP5
 2
A07
 72
hr
 868 2070 3486 0.5937 0.4590
MDA-MB-231 CP724714
10.0
uM
LJP5
 3
A07
 72
hr
 868 2476 3486 0.7102 0.6141
MDA-MB-231 CP466722
10.0
uM
LJP5
 1
I07
 72
hr
 868 1632 3486 0.4681 0.2918
MDA-MB-231 CP466722
10.0
uM
LJP5
 2
I07
 72
hr
 868 1891 3486 0.5424 0.3907
MDA-MB-231 CP466722
10.0
uM
LJP5
 3
I07
 72
hr
 868 1668 3486 0.4784 0.3055
MDA-MB-231 Crizotinib
10.0
uM
LJP5
 1
A19
 72
hr
 868 1079 3486 0.3095 0.0805
MDA-MB-231 Crizotinib
10.0
uM
LJP5
 2
A19
 72
hr
 868 1097 3486 0.3147 0.0874
MDA-MB-231 Crizotinib
10.0
uM
LJP5
 3
A19
 72
hr
 868 1084 3486 0.3109 0.0825
MDA-MB-231 Momelotinib
10.0
uM
LJP5
 1
P07
 72
hr
 868 807 3486 0.2315 -0.0233
MDA-MB-231 Momelotinib
10.0
uM
LJP5
 2
P07
 72
hr
 868 1040 3486 0.2983 0.0656
MDA-MB-231 Momelotinib
10.0
uM
LJP5
 3
P07
 72
hr
 868 972 3486 0.2788 0.0397
MDA-MB-231 Dasatinib
10.0
uM
LJP5
 1
D01
 72
hr
 868 617 3486 0.1770 -0.0959
MDA-MB-231 Dasatinib
10.0
uM
LJP5
 2
D01
 72
hr
 868 720 3486 0.2065 -0.0566
MDA-MB-231 Dasatinib
10.0
uM
LJP5
 3
D01
 72
hr
 868 564 3486 0.1618 -0.1162