Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Z-Leu-Leu-Norvalinal | HCC1806 | -4.1759 | 0.9667 | -5.9139 | -5.9076 | -5.9880 | 2.5020 | 0.0120 | 0.0120 | 5.6935 |
| Z-Leu-Leu-Norvalinal | MDA-MB-134-VI | -4.1759 | 0.9887 | -6.0569 | -6.0511 | -6.1492 | 3.9990 | 0.0278 | 0.0278 | 5.7423 |
| Z-Leu-Leu-Norvalinal | BT-483 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Z-Leu-Leu-Norvalinal | HCC1569 | -4.1759 | 0.9280 | -6.2469 | -6.1312 | -6.4100 | 1.3480 | 0.1512 | 0.1526 | 5.6524 |
| Z-Leu-Leu-Norvalinal | HCC38 | -4.1759 | 0.9811 | -6.1804 | -6.1801 | -6.2592 | 3.9990 | 0.0019 | 0.0019 | 5.5300 |
| Z-Leu-Leu-Norvalinal | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Z-Leu-Leu-Norvalinal | MDA-MB-231 | -4.1759 | 0.9916 | -6.0299 | -6.0271 | -6.0541 | 3.9990 | 0.0109 | 0.0109 | 5.9474 |
| Z-Leu-Leu-Norvalinal | BT-474 | -4.1759 | 0.9775 | -5.7444 | -5.6398 | -6.2190 | 1.4895 | 0.1463 | 0.1567 | 6.5937 |
| Z-Leu-Leu-Norvalinal | HCC1143 | -4.1759 | 0.9776 | -6.1579 | -6.1566 | -6.3208 | 1.6910 | 0.0020 | 0.0024 | 5.3934 |
| Z-Leu-Leu-Norvalinal | HCC1428 | -4.1759 | 0.9888 | -5.6669 | -5.4336 | -6.1560 | 3.1300 | 0.4069 | 0.4069 | 7.4502 |
| Z-Leu-Leu-Norvalinal | HCC1954 | -4.1759 | 0.9781 | -6.1469 | -6.1454 | -6.2118 | 3.3340 | 0.0072 | 0.0072 | 5.5164 |
| Z-Leu-Leu-Norvalinal | HCC202 | -4.1759 | 0.9849 | -6.1109 | -6.0129 | -6.5191 | 2.2650 | 0.1997 | 0.1997 | 6.2528 |
| Z-Leu-Leu-Norvalinal | HCC70 | -4.1759 | 0.9890 | -6.4969 | -6.4931 | -6.8051 | 2.8540 | 0.0120 | 0.0120 | 5.0384 |
| Z-Leu-Leu-Norvalinal | Hs 578T | -4.1759 | 0.9799 | -6.1834 | -6.1824 | -6.2573 | 3.7490 | 0.0043 | 0.0043 | 5.7867 |
| Z-Leu-Leu-Norvalinal | MCF7 | -4.1759 | 0.9820 | -5.6629 | -5.6560 | -5.8182 | 1.8940 | 0.0143 | 0.0158 | 6.2138 |
| Z-Leu-Leu-Norvalinal | SK-BR-3 | -4.1759 | 0.9890 | -6.0449 | -6.0270 | -6.1340 | 3.0140 | 0.0574 | 0.0574 | 5.9343 |
| Z-Leu-Leu-Norvalinal | AU565 | -4.1759 | 0.9822 | -6.2729 | -6.2668 | -6.3699 | 3.2500 | 0.0190 | 0.0190 | 5.4398 |
| Z-Leu-Leu-Norvalinal | BT-20 | -4.1759 | 0.9984 | -6.1669 | -6.1655 | -6.4118 | 3.2450 | 0.0036 | 0.0036 | 5.6428 |
| Z-Leu-Leu-Norvalinal | BT-549 | -4.1759 | 0.9881 | -6.4449 | -6.4452 | -6.5093 | 2.9590 | 0.0000 | 0.0000 | 5.0925 |
| Z-Leu-Leu-Norvalinal | CAMA-1 | -4.1759 | 0.9932 | -6.1179 | -6.1105 | -6.3269 | 2.5350 | 0.0220 | 0.0220 | 5.6478 |
| Z-Leu-Leu-Norvalinal | HCC1395 | -4.1759 | 0.7513 | -6.1219 | -6.0097 | -6.2038 | 3.9950 | 0.3221 | 0.3221 | 6.5143 |
| Z-Leu-Leu-Norvalinal | HCC1419 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Z-Leu-Leu-Norvalinal | HCC1937 | -4.1759 | 0.9971 | -6.0099 | -6.0088 | -6.3789 | 3.9990 | 0.0058 | 0.0058 | 5.9138 |
| Z-Leu-Leu-Norvalinal | MDA-MB-175-VII | -4.1759 | 0.9930 | -5.9949 | -5.9733 | -6.2188 | 2.9240 | 0.0548 | 0.0548 | 6.0043 |
| Z-Leu-Leu-Norvalinal | MDA-MB-157 | -4.1759 | 0.9623 | -6.2399 | -6.2359 | -6.4226 | 2.8140 | 0.0148 | 0.0148 | 5.4484 |